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Found 16 Enz. Inhib. hit(s) with all data for entry = 50038021
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50207805(20-(dimethylamino)-4,14,19,26-tetraazaheptacyclo[2...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50207804(20-(pyrrolidin-1-yl)-4,14,19,26-tetraazaheptacyclo...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50207808(33-(pyrrolidin-1-yl)-6,16,26,32-tetraazaheptacyclo...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50207807(31-(pyrrolidin-1-yl)-5,15,25,30-tetraazaheptacyclo...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50207806(31-(dimethylamino)-5,15,25,30-tetraazaheptacyclo[2...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human recombinant GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  48nMAssay Description:Inhibition of human Rsk3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  98nMAssay Description:Inhibition of human PKCthetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  510nMAssay Description:Inhibition of human MSK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  850nMAssay Description:Inhibition of human Rsk2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50207804(20-(pyrrolidin-1-yl)-4,14,19,26-tetraazaheptacyclo...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human recombinant PKCbeta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human recombinant PKCbeta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human Rsk1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50207807(31-(pyrrolidin-1-yl)-5,15,25,30-tetraazaheptacyclo...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human recombinant PKCbeta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50207805(20-(dimethylamino)-4,14,19,26-tetraazaheptacyclo[2...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of human recombinant PKCbeta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50371215(CHEMBL1162963)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human TrkBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed