Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50019851
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208318(SR-1459 | 1-(4-(1H-indazol-5-ylamino)piperidin-1-y...)
Affinity DataIC50: 13nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208323(SR-715 | 1-(4-(1H-indazol-5-ylamino)piperidin-1-yl...)
Affinity DataIC50: 80nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208321(SR-1362 | 1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208322(SR-899 | 1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(...)
Affinity DataIC50: 100nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208325(SR-1457 | 1-(4-(1H-indazol-5-ylamino)piperidin-1-y...)
Affinity DataIC50: 150nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208325(SR-1457 | 1-(4-(1H-indazol-5-ylamino)piperidin-1-y...)
Affinity DataIC50: 170nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208329(SR-890 | 1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(...)
Affinity DataIC50: 190nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208338(SR-1351 | 1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208320(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-2-(3...)
Affinity DataIC50: 250nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208334((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-(...)
Affinity DataIC50: 350nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208339((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-...)
Affinity DataIC50: 380nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208321(SR-1362 | 1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-...)
Affinity DataIC50: 410nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208326((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50: 450nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208330((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50: 470nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208328((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-...)
Affinity DataIC50: 470nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208318(SR-1459 | 1-(4-(1H-indazol-5-ylamino)piperidin-1-y...)
Affinity DataIC50: 490nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208338(SR-1351 | 1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-...)
Affinity DataIC50: 530nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208320(1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-2-(3...)
Affinity DataIC50: 760nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208337(SR-706 | (R)-1-(4-(1H-indazol-5-ylamino)piperidin-...)
Affinity DataIC50: 770nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208331((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-hydrox...)
Affinity DataIC50: 800nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208326((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50: 830nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208337(SR-706 | (R)-1-(4-(1H-indazol-5-ylamino)piperidin-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208317((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-h...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208336((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(3-chl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208330((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208335((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(2-chl...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208328((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208319(SR-709 | (S)-1-(4-(1H-indazol-5-ylamino)piperidin-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208334((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-(...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208329(SR-890 | 1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208336((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(3-chl...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208323(SR-715 | 1-(4-(1H-indazol-5-ylamino)piperidin-1-yl...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208332((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-hydrox...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208319(SR-709 | (S)-1-(4-(1H-indazol-5-ylamino)piperidin-...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208322(SR-899 | 1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208333((S)-(4-(1H-indazol-5-yl)piperazin-1-yl)(1,2,3,4-te...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208324((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208339((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-amino-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208335((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-(2-chl...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208324((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-a...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208327(SR-1360 | (R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208327(SR-1360 | (R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208331((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-hydrox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208317((S)-1-(4-(1H-indazol-5-ylamino)piperidin-1-yl)-2-h...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ROCK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208333((S)-(4-(1H-indazol-5-yl)piperazin-1-yl)(1,2,3,4-te...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50208332((R)-1-(4-(1H-indazol-5-yl)piperazin-1-yl)-2-hydrox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed