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Found 74 Enz. Inhib. hit(s) with all data for entry = 50019983
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209338(CHEMBL231102 | N-(2,6-difluorophenyl)-4-(2-methyl-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209370(4-(2-methyl-4-(6-(methylamino)pyrido[3,4-d]pyrimid...)
Affinity DataIC50:  13nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209341(4-(2-methyl-4-(6-(2-morpholinoethylamino)pyrido[3,...)
Affinity DataIC50:  15nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209340(4-(2-methyl-4-(6-(4-methylpiperazin-1-yl)pyrido[3,...)
Affinity DataIC50:  15nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209351(CHEMBL230575 | N-(3-(4-(4-(1-(3,3-dimethylbutanoyl...)
Affinity DataIC50:  16nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209338(CHEMBL231102 | N-(2,6-difluorophenyl)-4-(2-methyl-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209371(CHEMBL228276 | cyclopentyl(4-(2-methyl-4-(6-morpho...)
Affinity DataIC50:  18nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209372(CHEMBL230891 | N-tert-butyl-3-(4-(6-(3-(2-methoxya...)
Affinity DataIC50:  18nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209366(CHEMBL231101 | N-(2,6-difluorophenyl)-4-(4-(6,7-di...)
Affinity DataIC50:  19nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209348(1-(4-(4-(6-(2-methoxyethoxy)quinazolin-4-ylamino)-...)
Affinity DataIC50:  19nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209368(CHEMBL398172 | N-(2,6-difluorophenyl)-4-(4-(6-(dim...)
Affinity DataIC50:  20nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209368(CHEMBL398172 | N-(2,6-difluorophenyl)-4-(4-(6-(dim...)
Affinity DataIC50:  21nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209353(4-(2-methyl-4-(6-morpholinopyrido[3,4-d]pyrimidin-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209342(4-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazo...)
Affinity DataIC50:  23nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209352(3,3-dimethyl-1-(4-(2-methyl-4-(6-morpholinopyrido[...)
Affinity DataIC50:  23nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209353(4-(2-methyl-4-(6-morpholinopyrido[3,4-d]pyrimidin-...)
Affinity DataIC50:  24nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209364(CHEMBL231302 | N-(2,6-difluorophenyl)-4-(2-methyl-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209359(CHEMBL231205 | N-(2,6-difluorophenyl)-4-(4-(6-(2-m...)
Affinity DataIC50:  27nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209363(CHEMBL228275 | cyclopentyl(4-(4-(6-(2-methoxyethox...)
Affinity DataIC50:  29nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209372(CHEMBL230891 | N-tert-butyl-3-(4-(6-(3-(2-methoxya...)
Affinity DataIC50:  30nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209370(4-(2-methyl-4-(6-(methylamino)pyrido[3,4-d]pyrimid...)
Affinity DataIC50:  30nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209359(CHEMBL231205 | N-(2,6-difluorophenyl)-4-(4-(6-(2-m...)
Affinity DataIC50:  33nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209371(CHEMBL228276 | cyclopentyl(4-(2-methyl-4-(6-morpho...)
Affinity DataIC50:  33nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209360(CHEMBL230255 | N-(3-methyl-4-(1-methylpiperidin-4-...)
Affinity DataIC50:  34nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209358(4-(2-methyl-4-(6-(pyrrolidin-1-yl)pyrido[3,4-d]pyr...)
Affinity DataIC50:  36nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209363(CHEMBL228275 | cyclopentyl(4-(4-(6-(2-methoxyethox...)
Affinity DataIC50:  44nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209333(CHEMBL231204 | N-(2,6-difluorophenyl)-4-(4-(6-meth...)
Affinity DataIC50:  46nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209346(4-(4-(6-(dimethylamino)pyrido[3,4-d]pyrimidin-4-yl...)
Affinity DataIC50:  48nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209361(1-(4-(4-(6-(dimethylamino)pyrido[3,4-d]pyrimidin-4...)
Affinity DataIC50:  51nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209347(CHEMBL230574 | N-(3-{4-[4-(1-Cyclobutanecarbonyl-p...)
Affinity DataIC50:  51nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209350(CHEMBL388483 | N-(2,6-difluorophenyl)-4-(2-methyl-...)
Affinity DataIC50:  55nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209350(CHEMBL388483 | N-(2,6-difluorophenyl)-4-(2-methyl-...)
Affinity DataIC50:  55nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209366(CHEMBL231101 | N-(2,6-difluorophenyl)-4-(4-(6,7-di...)
Affinity DataIC50:  67nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209360(CHEMBL230255 | N-(3-methyl-4-(1-methylpiperidin-4-...)
Affinity DataIC50:  75nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209349(CHEMBL396287 | N-[3-(4-{4-[1-(3-Chloro-benzoyl)-pi...)
Affinity DataIC50:  75nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209362(1-(4-(4-(6,7-dimethoxyquinazolin-4-ylamino)-2-meth...)
Affinity DataIC50:  76nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209336(CHEMBL389457 | N-(2,6-difluorophenyl)-4-(4-(6-(3-(...)
Affinity DataIC50:  76nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209335((4-(4-(6,7-bis(2-methoxyethoxy)quinazolin-4-ylamin...)
Affinity DataIC50:  77nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209355(4-(4-(6,7-dimethoxyquinazolin-4-ylamino)-2-methylp...)
Affinity DataIC50:  77nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209351(CHEMBL230575 | N-(3-(4-(4-(1-(3,3-dimethylbutanoyl...)
Affinity DataIC50:  94nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209369(1-(4-(4-(6-methoxyquinazolin-4-ylamino)-2-methylph...)
Affinity DataIC50:  96nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209362(1-(4-(4-(6,7-dimethoxyquinazolin-4-ylamino)-2-meth...)
Affinity DataIC50:  100nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209344(3-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazo...)
Affinity DataIC50:  110nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209348(1-(4-(4-(6-(2-methoxyethoxy)quinazolin-4-ylamino)-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209340(4-(2-methyl-4-(6-(4-methylpiperazin-1-yl)pyrido[3,...)
Affinity DataIC50:  130nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209344(3-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazo...)
Affinity DataIC50:  130nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209342(4-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazo...)
Affinity DataIC50:  140nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209354(3-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazo...)
Affinity DataIC50:  140nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209347(CHEMBL230574 | N-(3-{4-[4-(1-Cyclobutanecarbonyl-p...)
Affinity DataIC50:  150nMAssay Description:Inhibition of erbB2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50209339(CHEMBL230786 | N-cyclobutyl-3-(4-(6-(3-(2-methoxya...)
Affinity DataIC50:  160nMAssay Description:Inhibition of erbB2 in NH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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