Compile Data Set for Download or QSAR
Report error Found 161 Enz. Inhib. hit(s) with all data for entry = 50020104
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210272BDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Flt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210309BDBM50210309(4-methyl-1-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3...)
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210300BDBM50210300(N-(3-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-di...)
Affinity DataIC50: 3nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210271BDBM50210271(7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210271BDBM50210271(7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Flt1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210272BDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Flt4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210271BDBM50210271(7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Flt4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210300BDBM50210300(N-(3-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-di...)
Affinity DataIC50: 5nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210299BDBM50210299(6-(2-(4-methylpiperazin-1-yl)ethyl)-3-(5-(3-phenox...)
Affinity DataIC50: 5nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210271BDBM50210271(7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...)
Affinity DataIC50: 5nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210272BDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)
Affinity DataIC50: 6nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210309BDBM50210309(4-methyl-1-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human KDR kinase by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210269BDBM50210269(4-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihyd...)
Affinity DataIC50: 8nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210277BDBM50210277(3-(5-(3-methoxyprop-1-ynyl)thiophen-3-yl)-6-((4-me...)
Affinity DataIC50: 8nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210272BDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)
Affinity DataIC50: 8nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210271BDBM50210271(7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...)
Affinity DataIC50: 9nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210293BDBM50210293(4-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human KDR kinase by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210272BDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)
Affinity DataIC50: 9nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210316BDBM50210316(3-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210284BDBM50210284(N,N-dimethyl-2-(3-(5-(3-phenoxyprop-1-ynyl)thiophe...)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210306BDBM50210306(6-(4-methylpiperazin-1-yl)-3-(5-(3-phenoxyprop-1-y...)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210296BDBM50210296(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210314BDBM50210314(6-((1-methylpiperidin-4-yl)methyl)-3-(5-(3-phenoxy...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human KDR kinase by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210306BDBM50210306(6-(4-methylpiperazin-1-yl)-3-(5-(3-phenoxyprop-1-y...)
Affinity DataIC50: 11nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210305BDBM50210305(1-(3-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-di...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human KDR kinase by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210285BDBM50210285(1-methyl-4-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human KDR kinase by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210271BDBM50210271(7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...)
Affinity DataIC50: 12nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210296BDBM50210296(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210303BDBM50210303(6-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...)
Affinity DataIC50: 14nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210289BDBM50210289(6-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-phenoxyp...)
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210305BDBM50210305(1-(3-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-di...)
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210271BDBM50210271(7-((1H-1,2,4-triazol-1-yl)methyl)-3-(5-(3-(2-metho...)
Affinity DataIC50: 16nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210285BDBM50210285(1-methyl-4-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3...)
Affinity DataIC50: 18nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210301BDBM50210301(6-((1H-pyrazol-1-yl)methyl)-3-(5-(3-phenoxyprop-1-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210293BDBM50210293(4-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210308BDBM50210308(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)
Affinity DataIC50: 22nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210277BDBM50210277(3-(5-(3-methoxyprop-1-ynyl)thiophen-3-yl)-6-((4-me...)
Affinity DataIC50: 23nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210316BDBM50210316(3-((3-(5-(3-phenoxyprop-1-ynyl)thiophen-3-yl)-1,4-...)
Affinity DataIC50: 24nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210295BDBM50210295(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)
Affinity DataIC50: 25nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210272BDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)
Affinity DataIC50: 26nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210275BDBM50210275(N-(3-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-di...)
Affinity DataIC50: 28nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210281BDBM50210281((4-methylpiperazin-1-yl)(3-(5-(3-phenoxyprop-1-yny...)
Affinity DataIC50: 29nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210297BDBM50210297(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)
Affinity DataIC50: 30nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210315BDBM50210315(3-(5-(3-(3,4-dimethylphenoxy)prop-1-ynyl)thiophen-...)
Affinity DataIC50: 33nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210315BDBM50210315(3-(5-(3-(3,4-dimethylphenoxy)prop-1-ynyl)thiophen-...)
Affinity DataIC50: 34nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210302BDBM50210302(3-(5-(3-(3-chlorophenoxy)prop-1-ynyl)thiophen-3-yl...)
Affinity DataIC50: 36nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210275BDBM50210275(N-(3-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-di...)
Affinity DataIC50: 36nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210270BDBM50210270(phenyl 3-(4-(6-((4-Methylpiperazin-1-yl)methyl)-1,...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human KDR kinase by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210269BDBM50210269(4-(4-(6-((4-methylpiperazin-1-yl)methyl)-1,4-dihyd...)
Affinity DataIC50: 40nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50210310BDBM50210310(6-(2-methoxyethoxy)-3-(5-(3-phenoxyprop-1-ynyl)thi...)
Affinity DataIC50: 40nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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