Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50020143
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210717(CHEMBL397275 | N1-((2S,3R)-4-(3-ethylbenzylamino)-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210721(CHEMBL397714 | N1-((2S,3R)-4-(3-ethylbenzylamino)-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210709(CHEMBL396765 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  11nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210719(3-(((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50:  30nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210715(CHEMBL230807 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  70nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210718(CHEMBL231646 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  90nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210722(CHEMBL231325 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  100nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210714(CHEMBL231542 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  100nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210713(CHEMBL394596 | ethyl 3-(((2S,3R)-4-(3-methoxybenzy...)
Affinity DataIC50:  132nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210717(CHEMBL397275 | N1-((2S,3R)-4-(3-ethylbenzylamino)-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210712(CHEMBL124380 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  250nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210720(CHEMBL397715 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  300nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210710(CHEMBL230190 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  360nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210714(CHEMBL231542 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  450nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210710(CHEMBL230190 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  570nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210718(CHEMBL231646 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  660nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210711(CHEMBL230314 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  770nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210713(CHEMBL394596 | ethyl 3-(((2S,3R)-4-(3-methoxybenzy...)
Affinity DataIC50:  866nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210721(CHEMBL397714 | N1-((2S,3R)-4-(3-ethylbenzylamino)-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210716(CHEMBL396010 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210709(CHEMBL396765 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210722(CHEMBL231325 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210719(3-(((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210712(CHEMBL124380 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210715(CHEMBL230807 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210720(CHEMBL397715 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210711(CHEMBL230314 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50210716(CHEMBL396010 | N1-((2S,3R)-4-(3-methoxybenzylamino...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed