Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50020323
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212488(4'-{7-methoxy-6-[(2-pyrrolidin-1-yl-ethylamino)-me...)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212496(3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-1,4-dihydro...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212497(CHEMBL234868 | [3-(4'-hydroxy-biphenyl-4-yl)-7-met...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212502(4'-{6-[(2-hydroxy-ethylamino)-methyl]-7-methoxy-1,...)
Affinity DataIC50:  0.430nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212505(4'-[7-methoxy-6-(4-methyl-piperazin-1-ylmethyl)-1,...)
Affinity DataIC50:  0.510nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212516(CHEMBL232808 | [3-(4'-hydroxy-biphenyl-4-yl)-7-met...)
Affinity DataIC50:  0.550nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212484(4'-{6-[(4-hydroxy-cyclohexylamino)-methyl]-7-metho...)
Affinity DataIC50:  0.560nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212491(CHEMBL234656 | N-[3-(4'-hydroxy-biphenyl-4-yl)-1,4...)
Affinity DataIC50:  0.740nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212503(3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-1,4-dihydro...)
Affinity DataIC50:  0.830nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212519(1-[3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-1,4-dihy...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212514(CHEMBL234654 | N-[3-(4'-hydroxy-biphenyl-4-yl)-1,4...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212501(2-butylamino-N-[3-(4'-hydroxy-biphenyl-4-yl)-1,4-d...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212520(CHEMBL444630 | [3-(4'-hydroxy-biphenyl-4-yl)-7-met...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212485(3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM91964(CHEMBL391449 | Chk1_95)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM91827(CHEMBL232804 | Chk1_101)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212498(3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212492(4'-{7-[(2-dimethylamino-ethylamino)-methyl]-1,4-di...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212487(CHEMBL232391 | N-[3-(4'-hydroxy-biphenyl-4-yl)-1,4...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212515(CHEMBL234482 | N-[3-(4'-hydroxy-biphenyl-4-yl)-1,4...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212500(4'-{7-[(2-pyrrolidin-1-yl-ethylamino)-methyl]-1,4-...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212489(4'-(6-(hydroxymethyl)-1,4-dihydroindeno[1,2-c]pyra...)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212495(4'-(5-(hydroxymethyl)-1,4-dihydroindeno[1,2-c]pyra...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212512(3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212486(4'-{7-[(2-hydroxy-ethylamino)-methyl]-1,4-dihydro-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212490(3-(4'-hydroxy-biphenyl-4-yl)-7-methoxy-4,4-dimethy...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212507(4'-[6-(4-methyl-piperazin-1-ylmethyl)-1,4-dihydro-...)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212506(3-(3'-fluoro-4'-hydroxy-biphenyl-4-yl)-7-methoxy-1...)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212509(3-fluoro-4'-[7-methoxy-6-(4-methyl-piperazin-1-ylm...)
Affinity DataIC50:  28nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212518(4'-[7-(tert-butylamino-methyl)-1,4-dihydro-indeno[...)
Affinity DataIC50:  34nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212510(CHEMBL232807 | [3-(4'-hydroxy-biphenyl-4-yl)-1,4-d...)
Affinity DataIC50:  91nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212513(4'-{5-[(2,2-dimethyl-propylamino)-methyl]-1,4-dihy...)
Affinity DataIC50:  209nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212517(3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...)
Affinity DataIC50:  671nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212494(4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-bipheny...)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212504(3-(3'-cyano-4'-hydroxy-biphenyl-4-yl)-7-methoxy-1,...)
Affinity DataIC50:  9.09E+3nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212521(3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212508(4-hydroxy-4'-[7-methoxy-6-(4-methyl-piperazin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50212493(3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant CHK-mediated Cdc25C phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed