Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 2858
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25418BDBM25418(2-(2,4-dichlorophenoxy)-5-(4-fluorophenyl)phenol |...)
Affinity DataIC50: 38nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25403BDBM25403(4‐(2,4‐dichlorophenoxy)‐3‐...)
Affinity DataIC50: 49nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25419BDBM25419(5-benzyl-2-(2,4-dichlorophenoxy)phenol | Triclosan...)
Affinity DataIC50: 71nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 8726BDBM8726(CHEMBL849 | TCL | 5-chloro-2-(2,4-dichlorophenoxy)...)
Affinity DataIC50: 73nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25420BDBM25420(2-(2,4-dichlorophenoxy)-5-(2-phenylethyl)phenol | ...)
Affinity DataIC50: 76nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25407BDBM25407(2‐(2,4‐dichlorophenoxy)‐5‐...)
Affinity DataIC50: 110nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25412BDBM25412(2-(2,4-dichlorophenoxy)-5-(3-methylbutyl)phenol | ...)
Affinity DataIC50: 120nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25402BDBM25402(2-(2,4-dichlorophenoxy)-5-phenylphenol | Triclosan...)
Affinity DataIC50: 140nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25410BDBM25410(2-(2,4-dichlorophenoxy)-5-(2-methylpropyl)phenol |...)
Affinity DataIC50: 180nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25417BDBM25417(2-(2,4-dichlorophenoxy)-5-(4-methylphenyl)phenol |...)
Affinity DataIC50: 190nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25401BDBM25401(2-(2,4-dichlorophenoxy)-5-methylphenol | Triclosan...)
Affinity DataIC50: 200nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25408BDBM25408(2-(2,4-dichlorophenoxy)-5-propylphenol | Triclosan...)
Affinity DataIC50: 210nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25416BDBM25416(2-(2,4-dichlorophenoxy)-5-(3-methylphenyl)phenol |...)
Affinity DataIC50: 230nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25411BDBM25411(2-(2,4-dichlorophenoxy)-5-(2-methylbutyl)phenol | ...)
Affinity DataIC50: 290nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25415BDBM25415(3-chloro-4-[2-hydroxy-4-(2-methylphenyl)phenoxy]be...)
Affinity DataIC50: 410nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25414BDBM25414(2-(2,4-dichlorophenoxy)-5-(2-methylphenyl)phenol |...)
Affinity DataIC50: 440nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25421BDBM25421(2-(2,4-dichlorophenoxy)-5-(3-phenylpropyl)phenol |...)
Affinity DataIC50: 440nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25409BDBM25409(5-butyl-2-(2,4-dichlorophenoxy)phenol | Triclosan ...)
Affinity DataIC50: 480nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25427BDBM25427(3-chloro-4-[2-hydroxy-4-(pyridin-4-ylmethyl)phenox...)
Affinity DataIC50: 530nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25413BDBM25413(5-(cyclohexylmethyl)-2-(2,4-dichlorophenoxy)phenol...)
Affinity DataIC50: 530nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25425BDBM25425(2-(2,4-dichlorophenoxy)-5-(pyridin-2-ylmethyl)phen...)
Affinity DataIC50: 640nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25422BDBM25422(3-chloro-4-[2-hydroxy-4-(pyridin-2-yl)phenoxy]benz...)
Affinity DataIC50: 700nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25426BDBM25426(2-(2,4-dichlorophenoxy)-5-(pyridin-3-ylmethyl)phen...)
Affinity DataIC50: 840nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25424BDBM25424(3-chloro-4-[2-hydroxy-4-(pyridin-4-yl)phenoxy]benz...)
Affinity DataIC50: 2.80E+3nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25405BDBM25405(4-(2,4-dichlorophenoxy)-3-hydroxybenzamide | Tricl...)
Affinity DataIC50: 2.10E+4nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25423BDBM25423(2-(2,4-dichlorophenoxy)-5-(pyridin-3-yl)phenol | T...)
Affinity DataIC50: 3.30E+4nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25404BDBM25404(2-(2,4-dichlorophenoxy)-5-(2H-1,2,3,4-tetrazol-5-y...)
Affinity DataIC50: 1.00E+5nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed
TargetEnoyl-ACP reductase(malaria parasite P. falciparum)
Jacobus Pharmaceutical

LigandChemical structure of BindingDB Monomer ID 25406BDBM25406(4-(2,4-dichlorophenoxy)-3-hydroxybenzoic acid | CH...)
Affinity DataIC50: 1.00E+5nMpH: 7.9 T: 2°CAssay Description:PfENR inhibition assays were carried out on a Cary 100 Bio Spectrophotometer or POLARstar Optima by monitoring oxidation of NADH at 340 nm. The IC50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2008
Entry Details Article
PubMed