Compile Data Set for Download or QSAR
maximum 50k data
Found 39 Enz. Inhib. hit(s) with all data for entry = 50020630
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215757(3-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215752(6-(4-methylpiperazin-1-yl)-2-(4-(2-(pyridin-3-yl)v...)
Affinity DataIC50:  290nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215749(4-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215746(6-methoxy-2-(4-(2-(5-methoxypyridin-3-yl)vinyl)-1H...)
Affinity DataIC50:  400nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215750(6-methoxy-2-(4-(2-(pyridin-3-yl)vinyl)-1H-pyrazol-...)
Affinity DataIC50:  510nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215754(4-(2-(3-(6-methoxy-1H-benzo[d]imidazol-2-yl)-1H-py...)
Affinity DataIC50:  530nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215756(6-methoxy-2-(4-(2-(4-methylpyridin-3-yl)vinyl)-1H-...)
Affinity DataIC50:  550nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215753(CHEMBL245967 | N-((5-(2-(3-(6-methoxy-1H-benzo[d]i...)
Affinity DataIC50:  590nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215754(4-(2-(3-(6-methoxy-1H-benzo[d]imidazol-2-yl)-1H-py...)
Affinity DataIC50:  610nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215746(6-methoxy-2-(4-(2-(5-methoxypyridin-3-yl)vinyl)-1H...)
Affinity DataIC50:  650nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215756(6-methoxy-2-(4-(2-(4-methylpyridin-3-yl)vinyl)-1H-...)
Affinity DataIC50:  760nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215753(CHEMBL245967 | N-((5-(2-(3-(6-methoxy-1H-benzo[d]i...)
Affinity DataIC50:  820nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215750(6-methoxy-2-(4-(2-(pyridin-3-yl)vinyl)-1H-pyrazol-...)
Affinity DataIC50:  970nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215755(CHEMBL397549 | methyl 5-(2-(3-(6-methoxy-1H-benzo[...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215745(CHEMBL245966 | N-ethyl-5-(2-(3-(6-methoxy-1H-benzo...)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215747(5-(2-(3-(6-methoxy-1H-benzo[d]imidazol-2-yl)-1H-py...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215753(CHEMBL245967 | N-((5-(2-(3-(6-methoxy-1H-benzo[d]i...)
Affinity DataIC50:  3.03E+3nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215749(4-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-...)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215747(5-(2-(3-(6-methoxy-1H-benzo[d]imidazol-2-yl)-1H-py...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215752(6-(4-methylpiperazin-1-yl)-2-(4-(2-(pyridin-3-yl)v...)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215748(CHEMBL245376 | N-((5-(2-(3-(4-(trifluoromethyl)-1H...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215751(2-(4-(2-(pyridin-3-yl)vinyl)-1H-pyrazol-3-yl)-1H-i...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215756(6-methoxy-2-(4-(2-(4-methylpyridin-3-yl)vinyl)-1H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215751(2-(4-(2-(pyridin-3-yl)vinyl)-1H-pyrazol-3-yl)-1H-i...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215750(6-methoxy-2-(4-(2-(pyridin-3-yl)vinyl)-1H-pyrazol-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215752(6-(4-methylpiperazin-1-yl)-2-(4-(2-(pyridin-3-yl)v...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215748(CHEMBL245376 | N-((5-(2-(3-(4-(trifluoromethyl)-1H...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215746(6-methoxy-2-(4-(2-(5-methoxypyridin-3-yl)vinyl)-1H...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215757(3-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215749(4-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-...)
Affinity DataIC50:  3.27E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215745(CHEMBL245966 | N-ethyl-5-(2-(3-(6-methoxy-1H-benzo...)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215751(2-(4-(2-(pyridin-3-yl)vinyl)-1H-pyrazol-3-yl)-1H-i...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215755(CHEMBL397549 | methyl 5-(2-(3-(6-methoxy-1H-benzo[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215747(5-(2-(3-(6-methoxy-1H-benzo[d]imidazol-2-yl)-1H-py...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215754(4-(2-(3-(6-methoxy-1H-benzo[d]imidazol-2-yl)-1H-py...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215755(CHEMBL397549 | methyl 5-(2-(3-(6-methoxy-1H-benzo[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215745(CHEMBL245966 | N-ethyl-5-(2-(3-(6-methoxy-1H-benzo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of aurora-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215757(3-(2-(3-(4-(trifluoromethyl)-1H-imidazol-2-yl)-1H-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50215748(CHEMBL245376 | N-((5-(2-(3-(4-(trifluoromethyl)-1H...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed