Compile Data Set for Download or QSAR
Report error Found 79 Enz. Inhib. hit(s) with all data for entry = 50020824
LigandChemical structure of BindingDB Monomer ID 50218023BDBM50218023({[2-(5-benzo[1,3]dioxol-5-yl-2'-chloro-biphenyl-2-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218032BDBM50218032(({2-[2'-chloro-5-(2,3-dihydro-benzofuran-5-yl)-bip...)
Affinity DataIC50: 13nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218017BDBM50218017(({2-[2'-chloro-5-(2,3-dihydro-benzo[1,4]dioxin-6-y...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218012BDBM50218012(({2-[4-(2,3-dihydro-benzofuran-5-yl)-2-thiophen-2-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218004BDBM50218004(({2-[4'-methoxy-3'-methyl-3-(thiophene-2-carbonyl)...)
Affinity DataIC50: 18nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218001BDBM50218001(({2-[4-benzo[1,3]dioxol-5-yl-2-(thiophene-2-carbon...)
Affinity DataIC50: 19nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218016BDBM50218016(({2-[4-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-2-thiop...)
Affinity DataIC50: 25nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218007BDBM50218007(({2-[3'-chloro-3-(thiophene-2-carbonyl)-biphenyl-4...)
Affinity DataIC50: 26nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218021BDBM50218021(({2-[4'-methoxy-3-(thiophene-2-carbonyl)-biphenyl-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218005BDBM50218005({[2-(2''-chloro-4-methoxy-3-methyl-[1,1';3',1'']te...)
Affinity DataIC50: 28nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218002BDBM50218002({[2-(4-benzo[1,3]dioxol-5-yl-2-thiophen-2-yl-pheno...)
Affinity DataIC50: 34nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218014BDBM50218014({methyl-[2-(3-thiophen-2-ylmethyl-biphenyl-4-yloxy...)
Affinity DataIC50: 40nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218003BDBM50218003((methyl-{2-[3'-methyl-3-(thiophene-2-carbonyl)-bip...)
Affinity DataIC50: 45nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217995BDBM50217995((methyl-{2-[3-(thiophene-2-carbonyl)-biphenyl-4-yl...)
Affinity DataIC50: 45nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218022BDBM50218022({[2-(2''-chloro-[1,1';3',1'']terphenyl-4'-yloxy)-e...)
Affinity DataIC50: 53nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217996BDBM50217996({methyl-[2-(2''-methyl-[1,1';3',1'']terphenyl-4'-y...)
Affinity DataIC50: 56nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218033BDBM50218033((methyl-{2-[4'-methyl-3-(thiophene-2-carbonyl)-bip...)
Affinity DataIC50: 59nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217998BDBM50217998({[2-(3-benzoyl-biphenyl-4-yloxy)-ethyl]-methyl-ami...)
Affinity DataIC50: 65nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217997BDBM50217997(({2-[4'-chloro-3-(thiophene-2-carbonyl)-biphenyl-4...)
Affinity DataIC50: 68nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218009BDBM50218009({[2-(3-cyclohexanecarbonyl-biphenyl-4-yloxy)-ethyl...)
Affinity DataIC50: 70nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218030BDBM50218030({methyl-[2-(3-thiophen-2-yl-biphenyl-4-yloxy)-ethy...)
Affinity DataIC50: 70nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218025BDBM50218025(({2-[3',4'-dimethyl-3-(thiophene-2-carbonyl)-biphe...)
Affinity DataIC50: 76nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218028BDBM50218028({[2-(3-benzyl-biphenyl-4-yloxy)-ethyl]-methyl-amin...)
Affinity DataIC50: 85nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218029BDBM50218029(({2-[3'-methoxy-3-(thiophene-2-carbonyl)-biphenyl-...)
Affinity DataIC50: 104nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218000BDBM50218000({[2-(2''-fluoro-[1,1';3',1'']terphenyl-4'-yloxy)-e...)
Affinity DataIC50: 108nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218026BDBM50218026({methyl-[2-(3-thiophen-3-yl-biphenyl-4-yloxy)-ethy...)
Affinity DataIC50: 139nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218013BDBM50218013({[2-(4'-methoxy-3'-methyl-3-thiophen-2-yl-biphenyl...)
Affinity DataIC50: 161nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218027BDBM50218027(({2-[2'-chloro-3-(thiophene-2-carbonyl)-biphenyl-4...)
Affinity DataIC50: 175nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218020BDBM50218020({methyl-[2-([1,1';3',1'']terphenyl-4'-yloxy)-ethyl...)
Affinity DataIC50: 229nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217999BDBM50217999({[2-(3-cyclohexyl-biphenyl-4-yloxy)-ethyl]-methyl-...)
Affinity DataIC50: 251nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218024BDBM50218024({[2-(3-cyclohexylmethyl-biphenyl-4-yloxy)-ethyl]-m...)
Affinity DataIC50: 289nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218018BDBM50218018({[2-(2''-methoxy-[1,1';3',1'']terphenyl-4'-yloxy)-...)
Affinity DataIC50: 351nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218011BDBM50218011({methyl-[2-(3-naphthalen-1-yl-biphenyl-4-yloxy)-et...)
Affinity DataIC50: 496nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218006BDBM50218006((methyl-{2-[2'-methyl-3-(thiophene-2-carbonyl)-bip...)
Affinity DataIC50: 632nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218031BDBM50218031({[2-(3''-chloro-[1,1';3',1'']terphenyl-4'-yloxy)-e...)
Affinity DataIC50: 674nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218015BDBM50218015((methyl-{2-[2-(thiophene-2-carbonyl)-4-trifluorome...)
Affinity DataIC50: 702nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218019BDBM50218019(({2-[3',4'-dimethoxy-3-(thiophene-2-carbonyl)-biph...)
Affinity DataIC50: 834nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218010BDBM50218010({methyl-[2-(3-thiazol-2-yl-biphenyl-4-yloxy)-ethyl...)
Affinity DataIC50: 957nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218008BDBM50218008({[2-(4''-chloro-[1,1';3',1'']terphenyl-4'-yloxy)-e...)
Affinity DataIC50: 965nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT1 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218026BDBM50218026({methyl-[2-(3-thiophen-3-yl-biphenyl-4-yloxy)-ethy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218021BDBM50218021(({2-[4'-methoxy-3-(thiophene-2-carbonyl)-biphenyl-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217998BDBM50217998({[2-(3-benzoyl-biphenyl-4-yloxy)-ethyl]-methyl-ami...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218007BDBM50218007(({2-[3'-chloro-3-(thiophene-2-carbonyl)-biphenyl-4...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218016BDBM50218016(({2-[4-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-2-thiop...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218022BDBM50218022({[2-(2''-chloro-[1,1';3',1'']terphenyl-4'-yloxy)-e...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218031BDBM50218031({[2-(3''-chloro-[1,1';3',1'']terphenyl-4'-yloxy)-e...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217995BDBM50217995((methyl-{2-[3-(thiophene-2-carbonyl)-biphenyl-4-yl...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50149871BDBM50149871((R)-2-((3-(biphenyl-4-yloxy)-3-(4-fluorophenyl)pro...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50217996BDBM50217996({methyl-[2-(2''-methyl-[1,1';3',1'']terphenyl-4'-y...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50218027BDBM50218027(({2-[2'-chloro-3-(thiophene-2-carbonyl)-biphenyl-4...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [14C]glycine reuptake at human GlyT2 expressed in BE(2)-C cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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