Compile Data Set for Download or QSAR
maximum 50k data
Found 92 Enz. Inhib. hit(s) with all data for entry = 50020856
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218305(3-chloro-N-((1S,2R)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  0.210nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218298(5-chloro-N-((1S,2R)-1-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  0.270nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218280(5-chloro-N-((3R,4S)-1-(2-methoxyacetyl)-4-(4-(2-ox...)
Affinity DataKi:  0.360nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218315((3R,4S)-methyl 3-(2-chlorothiophene-5-carboxamido)...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216554(5-CHLORO-N-((1R,2S)-2-(4-(2-OXOPYRIDIN-1(2H)-YL)BE...)
Affinity DataKi:  0.430nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218308(5-chloro-N-((3R,4S)-1-(methylsulfonyl)-4-(4-(2-oxo...)
Affinity DataKi:  0.440nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  0.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218312((1S,3R,4S)-methyl 3-(2-chlorothiophene-5-carboxami...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218300((3R,4S)-3-(2-chlorothiophene-5-carboxamido)-N,N-di...)
Affinity DataKi:  0.560nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218290(5-chloro-N-((1R,2S,4S)-4-(hydroxymethyl)-2-(4-(2-o...)
Affinity DataKi:  0.560nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(CHEMBL394129 | N-((3R,4S)-1-acetyl-4-(4-(2-oxopyri...)
Affinity DataKi:  0.580nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218283(5-chloro-N-((3R,4S)-1-(ethylsulfonyl)-4-(4-(2-oxop...)
Affinity DataKi:  0.640nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50216604(3-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  0.730nMAssay Description:Inhibition of human factor 10a in presence of tripeptide substrate at 25 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218306((3R,4S)-methyl 3-(2-chlorothiophene-5-carboxamido)...)
Affinity DataKi:  0.740nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218319(3-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  0.840nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218294((3R,4S)-2-methoxyethyl 3-(2-chlorothiophene-5-carb...)
Affinity DataKi:  0.930nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218301(3-chloro-N-((1S,2R)-1-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  1nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218286((3R,4S)-3-(2-chlorothiophene-5-carboxamido)-N-meth...)
Affinity DataKi:  1.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218295(5-chloro-N-((3R,4S)-1-isobutyryl-4-(4-(2-oxopyridi...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218314(5-chloro-N-((1R,2S,4S)-4-(morpholine-4-carbonyl)-2...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218284(5-chloro-N-((1R,2S,4S)-4-(cyclopropylcarbamoyl)-2-...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218281(5-chloro-N-((3R,4S)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218304(5-chloro-N-((3R,4S)-1-(isopropylsulfonyl)-4-(4-(2-...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218296(5-chloro-N-((3R,4S)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218287((1S,3R,4S)-3-(2-chlorothiophene-5-carboxamido)-4-(...)
Affinity DataKi:  1.90nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218320(5-chloro-N-((3R,4S)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  2nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218310(5-chloro-N-((3R,4S)-1-(cyclopropanecarbonyl)-4-(4-...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218297(5-chloro-N-((1R,2S,4S)-4-(dimethylcarbamoyl)-2-(4-...)
Affinity DataKi:  2.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218307(CHEMBL235150 | N-((3R,4S)-1-benzoyl-4-(4-(2-oxopyr...)
Affinity DataKi:  2.20nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218285(5-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218318(3-chloro-N-((3S,4R)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  2.60nMAssay Description:Inhibition of human factor 10a in presence of tripeptide substrate at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218317((3R,4S)-ethyl 3-(3-chloro-1H-indole-6-carboxamido)...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218302(CHEMBL445941 | N-((1R,2S,4S)-4-((2-methoxyethyl)ca...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218299((3R,4S)-methyl 3-(3-chloro-1H-indole-6-carboxamido...)
Affinity DataKi:  3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218292(CHEMBL237924 | N-((3R,4S)-1-acetyl-4-(4-(2-oxopyri...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218311((3R,4S)-(9H-fluoren-9-yl)methyl 3-(2-chlorothiophe...)
Affinity DataKi:  4.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  7.5nMAssay Description:Inhibition of human factor 10a in presence of prothrombin at 25 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218321(3-chloro-N-((1R,2S)-1-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  7.90nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218288(5-chloro-N-((3R,4S)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  9.5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218293(3-chloro-N-((3R,4S)-4-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  18nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218303(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  27nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  30nMAssay Description:Inhibition of human factor 10a in presence of saturating prothrombin at 37 degCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218309((3R,4S)-(9H-fluoren-9-yl)methyl 3-(3-chloro-1H-ind...)
Affinity DataKi:  163nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218289(5-chloro-N-((1S,2R)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Affinity DataKi:  230nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218283(5-chloro-N-((3R,4S)-1-(ethylsulfonyl)-4-(4-(2-oxop...)
Affinity DataKi:  3.95E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218282((3R,4S)-ethyl 3-(2-chlorothiophene-5-carboxamido)-...)
Affinity DataKi:  4.02E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218291(CHEMBL394129 | N-((3R,4S)-1-acetyl-4-(4-(2-oxopyri...)
Affinity DataKi:  5.44E+3nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50218287((1S,3R,4S)-3-(2-chlorothiophene-5-carboxamido)-4-(...)
Affinity DataKi: >6.00E+3nMAssay Description:Inhibition of human plasma kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 92 total ) | Next | Last >>
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