Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for entry = 50020943
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219260(5-(3-cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimida...)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity to cytosolic PR in T47D cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219263(3-[3-(1-ethylpropyl)-2-thioxo-2,3-dihydro-1H-benzi...)
Affinity DataIC50:  3.60nMAssay Description:Antagonist activity at progesterone receptor expressed in T47D cells assesed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169354(5-(3-Cyclopentyl-2-oxo-2,3-dihydro-1H-benzoimidazo...)
Affinity DataIC50:  5.60nMAssay Description:Antagonist activity at progesterone receptor expressed in T47D cells assesed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219259(5-(3-Cyclobutyl-2-oxo-2,3-dihydro-1H-benzoimidazol...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at progesterone receptor expressed in T47D cells assesed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219265(5-[3-(1-ethylpropyl)-2-oxo-2,3-dihydro-1H-benzimid...)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at progesterone receptor expressed in T47D cells assesed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169354(5-(3-Cyclopentyl-2-oxo-2,3-dihydro-1H-benzoimidazo...)
Affinity DataIC50:  26nMAssay Description:Binding affinity to cytosolic PR in T47D cells by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219262(6-(3-chloro-4-fluorophenyl)-1-(1-ethylpropyl)-1,3-...)
Affinity DataIC50:  34nMAssay Description:Antagonist activity at progesterone receptor expressed in T47D cells assesed as inhibition of progesterone-induced alkaline phosphatase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219260(5-(3-cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimida...)
Affinity DataIC50:  99nMAssay Description:Antagonist activity at glucocorticoid receptor expressed in L929 cells by HRE-tk luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219260(5-(3-cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimida...)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at androgen receptor expressed in A549 cells by HRE-tk luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219261(5-(3-cyclobutyl-2-thioxo-2,3-dihydro-1H-benzimidaz...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219260(5-(3-cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimida...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at glucocorticoid receptor expressed in L929 cells by HRE-tk luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50169354(5-(3-Cyclopentyl-2-oxo-2,3-dihydro-1H-benzoimidazo...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219264(5-[3-(1-ethylpropyl)-2-thioxo-2,3-dihydro-1H-benzi...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219260(5-(3-cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimida...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at androgen receptor expressed in A549 cells by HRE-tk luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219263(3-[3-(1-ethylpropyl)-2-thioxo-2,3-dihydro-1H-benzi...)
Affinity DataEC50:  270nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219265(5-[3-(1-ethylpropyl)-2-oxo-2,3-dihydro-1H-benzimid...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219259(5-(3-Cyclobutyl-2-oxo-2,3-dihydro-1H-benzoimidazol...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219266(1-cyclopentyl-6-(3,4-difluorophenyl)-1,3-dihydro-2...)
Affinity DataEC50:  63nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219267(3-(3-cyclobutyl-2-thioxo-2,3-dihydro-1H-benzimidaz...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219257(6-(3-chloro-4-fluorophenyl)-1-cyclopentyl-1,3-dihy...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50219260(5-(3-cyclopentyl-2-thioxo-2,3-dihydro-1H-benzimida...)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at progesterone receptor expressed in T47D cells by alkaline phosphatase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed