Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 2460
LigandChemical structure of BindingDB Monomer ID 20832BDBM20832(7-fluoro-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2...)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
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Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20833BDBM20833(7-bromo-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2,...)
Affinity DataIC50: 38nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20832BDBM20832(7-fluoro-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2...)
Affinity DataIC50: 52nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20838BDBM20838(7-(morpholin-4-ylmethyl)-3-[2-(pyridin-4-yl)-1,3-t...)
Affinity DataIC50: 62nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20830BDBM20830(6-fluoro-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2...)
Affinity DataIC50: 72nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20820BDBM20820(3-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]-1,2,3,4-tetr...)
Affinity DataIC50: 77nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20819BDBM20819(3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2,3,4-tetr...)
Affinity DataIC50: 79nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20834BDBM20834(7-phenyl-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2...)
Affinity DataIC50: 113nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20819BDBM20819(3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2,3,4-tetr...)
Affinity DataIC50: 142nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20831BDBM20831(6-methyl-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2...)
Affinity DataIC50: 165nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20827BDBM20827(5-bromo-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2,...)
Affinity DataIC50: 228nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20825BDBM20825(5-fluoro-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2...)
Affinity DataIC50: 240nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20837BDBM20837(5-(morpholin-4-ylmethyl)-3-[2-(pyridin-4-yl)-1,3-t...)
Affinity DataIC50: 284nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20826BDBM20826(5-chloro-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2...)
Affinity DataIC50: 332nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20829BDBM20829(5-methoxy-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,...)
Affinity DataIC50: 362nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20839BDBM20839(3-[4-(pyridin-3-yl)-1,3-thiazol-2-yl]-1,2,3,4-tetr...)
Affinity DataIC50: 399nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20838BDBM20838(7-(morpholin-4-ylmethyl)-3-[2-(pyridin-4-yl)-1,3-t...)
Affinity DataIC50: 529nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20822BDBM20822(3-[3-(pyridin-4-yl)-1,2,4-thiadiazol-5-yl]-1,2,3,4...)
Affinity DataIC50: 616nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20841BDBM20841(3-[2-(2-ethylpyridin-4-yl)-1,3-thiazol-4-yl]-1,2,3...)
Affinity DataIC50: 746nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20835BDBM20835(5-(4-methylpiperazin-1-yl)-3-[2-(pyridin-4-yl)-1,3...)
Affinity DataIC50: 829nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20818BDBM20818(1-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-2,3-dihydro-...)
Affinity DataIC50: 1.16E+3nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20836BDBM20836(6-(4-methylpiperazin-1-yl)-3-[2-(pyridin-4-yl)-1,3...)
Affinity DataIC50: 1.17E+3nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20828BDBM20828(5-methyl-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2...)
Affinity DataIC50: 1.26E+3nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20816BDBM20816(1-phenyl-3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]urea...)
Affinity DataIC50: 2.99E+3nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20840BDBM20840(3-[4-(pyridin-2-yl)-1,3-thiazol-2-yl]-1,2,3,4-tetr...)
Affinity DataIC50: 7.36E+3nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20817BDBM20817(3-[2-(pyridin-4-yl)-1,3-thiazol-4-yl]-1,2,3,4-tetr...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20821BDBM20821(3-[3-(pyridin-4-yl)-1,2,4-oxadiazol-5-yl]-1,2,3,4-...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20823BDBM20823(3-[5-(pyridin-4-yl)thiophen-2-yl]-1,2,3,4-tetrahyd...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 20824BDBM20824(3-[3-(pyridin-4-yl)phenyl]-1,2,3,4-tetrahydroquina...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 25 °C with substrate, and test compounds in the presence of ATP/ [gamma-33P] ATP. 33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed