Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50021096
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35909(Eulexin | 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...)
Affinity DataIC50: 31nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220941(5-(4-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 96nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220939(6-(3-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 120nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220934(3-(4-(3-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220937(8-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-...)
Affinity DataIC50: 190nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM35909(Eulexin | 2-hydroxy-2-methyl-N-(4-nitro-3-(trifluo...)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220941(5-(4-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220937(8-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-...)
Affinity DataIC50: 260nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220934(3-(4-(3-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220936(5-(4-(3-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220945(5-(3-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 330nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220940(10-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13...)
Affinity DataIC50: 350nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220945(5-(3-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 350nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220933(10-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13...)
Affinity DataIC50: 410nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220947(6-(4-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220943(4-(4-(3-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 430nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220939(6-(3-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 530nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220944(10-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17...)
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220936(5-(4-(3-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 660nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220943(4-(4-(3-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 660nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220938(8-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-...)
Affinity DataIC50: 660nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220935(4-(3-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 670nMAssay Description:Displacement of [3H]mibolerone from human androgen receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220938(8-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-...)
Affinity DataIC50: 730nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220942(4-(4-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 850nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220940(10-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13...)
Affinity DataIC50: 920nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220935(4-(3-(4-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 920nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220944(10-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13,17...)
Affinity DataIC50: 2.00E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220946(4-(3-(3-((7R,8R,9S,10R,13S,14S,17S)-17-hydroxy-10,...)
Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50220933(10-((5S,7R,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human androgen receptor expressed in HeLa cells assessed as inhibition of dihydrotestosterone induced transcriptional activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed