Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 2233
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18337BDBM18337((2S,4S,5S,7S)-5-amino-N-[2,2-dimethyl-2-(methylcar...)
Affinity DataIC50: 0.400nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18342BDBM18342((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 0.400nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 17950BDBM17950(CHEMBL1639 | Rasilez | (2S,4S,5S,7S)-5-amino-N-(2-...)
Affinity DataIC50: 0.600nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18340BDBM18340((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 0.600nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18344BDBM18344((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 0.600nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18323BDBM18323((2S,4S,5S,7S)-5-amino-N-(3-carbamoylpropyl)-4-hydr...)
Affinity DataIC50: 0.700nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18338BDBM18338((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 0.800nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18326BDBM18326((2S,4S,5S,7S)-5-amino-N-[(1S)-1-carbamoylpropyl]-4...)
Affinity DataIC50: 0.800nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18334BDBM18334((2S,4S,5S,7S)-5-amino-N-[(2R)-2-carbamoyl-2-methyl...)
Affinity DataIC50: 0.900nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18336BDBM18336((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 0.900nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18333BDBM18333((2S,4S,5S,7S)-5-amino-N-[(2S)-2-carbamoyl-2-methyl...)
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18335BDBM18335((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18350BDBM18350((2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethyle...)
Affinity DataIC50: 1nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18321BDBM18321((2S,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-{[4-meth...)
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18322BDBM18322((2S,4S,5S,7S)-5-amino-N-(2-carbamoylethyl)-4-hydro...)
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18339BDBM18339((2S,4S,5S,7S)-5-amino-N-[3-(dimethylcarbamoyl)prop...)
Affinity DataIC50: 1nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18331BDBM18331((2S,4S,5S,7S)-5-amino-N-[(2S)-1-carbamoylpropan-2-...)
Affinity DataIC50: 1nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18348BDBM18348((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18349BDBM18349((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(4...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18341BDBM18341((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 2nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18327BDBM18327((2S,4S,5S,7S)-5-amino-N-[(1S)-1-carbamoyl-2-hydrox...)
Affinity DataIC50: 2nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18324BDBM18324((2S,4S,5S,7S)-5-amino-N-(carbamoylmethyl)-4-hydrox...)
Affinity DataIC50: 3nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18343BDBM18343((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 3nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18329BDBM18329((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 3nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18330BDBM18330((2S,4S,5S,7S)-5-amino-N-[2-(dimethylcarbamoyl)ethy...)
Affinity DataIC50: 3nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18346BDBM18346((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 3nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18347BDBM18347(3-[(2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3...)
Affinity DataIC50: 3nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18325BDBM18325((2S,4S,5S,7S)-5-amino-N-[(1S)-1-carbamoylethyl]-4-...)
Affinity DataIC50: 4nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18332BDBM18332((2S,4S,5S,7S)-5-amino-N-[(2R)-1-carbamoylpropan-2-...)
Affinity DataIC50: 6nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18328BDBM18328((2S,4S,5S,7S)-5-amino-N-(1-carbamoyl-1-methylethyl...)
Affinity DataIC50: 13nMpH: 7.2 T: 2°CAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed
TargetRenin(Human)
Novartis Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 18345BDBM18345((2S,4S,5S,7S)-5-amino-4-hydroxy-7-{[4-methoxy-3-(3...)
Affinity DataIC50: 16nMAssay Description:Enzyme inhibition by test compounds was determined using human recombinant renin, incubating with a synthetic tetradecapeptide substrate. The Ang I g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2007
Entry Details Article
PubMed