Compile Data Set for Download or QSAR
maximum 50k data
Found 20 Enz. Inhib. hit(s) with all data for entry = 50021239
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222489((R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  2nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222495((S)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222493((R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)
Affinity DataIC50:  4nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222489((R)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222493((R)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  11nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222492((S)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  19nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222494((S)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  22nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)
Affinity DataIC50:  35nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)
Affinity DataIC50:  43nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222490((R)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50:  97nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222492((S)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  131nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222490((R)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50:  147nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222494((S)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  191nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222495((S)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50:  259nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222494((S)-N-(2-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  291nMAssay Description:Inhibition of Erb2 autophosphorylation by cellular clone 24 assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222495((S)-1-(2-((4-(3-chloro-4-(pyridin-2-ylmethoxy)phen...)
Affinity DataIC50:  327nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222491(CHEMBL249928 | N-(2-(4-(3-chloro-4-(pyridin-2-ylme...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of KdrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50222492((S)-N-(1-(4-(3-chloro-4-(pyridin-2-ylmethoxy)pheny...)
Affinity DataIC50:  2.58E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed