Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 50030315
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294207(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: >1.60E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294205(1-(1-cyclohexylphthalazin-2(1H)-yl)-3-(5-((2,4-dia...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294204(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294210(1-(1-butylphthalazin-2(1H)-yl)-3-(5-((2,4-diaminop...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294212(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-3-methoxy...)
Affinity DataIC50: >2.10E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294206(1-(1-cyclopentylphthalazin-2(1H)-yl)-3-(5-((2,4-di...)
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294215(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: >2.20E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294216(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: >2.30E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294213(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2-hydroxy...)
Affinity DataIC50: >2.40E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294209(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294207(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294205(1-(1-cyclohexylphthalazin-2(1H)-yl)-3-(5-((2,4-dia...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294204(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294203(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294211(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-3-hydroxy...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294210(1-(1-butylphthalazin-2(1H)-yl)-3-(5-((2,4-diaminop...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294209(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294208(CHEMBL565059 | methyl 2-(2-(3-(5-((2,4-diaminopyri...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294206(1-(1-cyclopentylphthalazin-2(1H)-yl)-3-(5-((2,4-di...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294203(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: >2.70E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294217(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: >2.80E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294214(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: >4.20E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294211(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-3-hydroxy...)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294208(CHEMBL565059 | methyl 2-(2-(3-(5-((2,4-diaminopyri...)
Affinity DataIC50:  8.13E+5nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed