Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50021467
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50163251BDBM50163251(2-(4-(4-hydroxyphenylthio)phenyl)-1H-benzo[d]imida...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225014BDBM50225014(2-(4-((1-(4-chlorobenzyl)piperidin-3-yl)methoxy)ph...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34064BDBM34064(CHEMBL179583 | 2-arylbenzimidazole)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225008BDBM50225008(2-(4-(2-(1-benzoylpiperidin-4-yl)ethoxy)phenyl)-1H...)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225005BDBM50225005(2-(4-((1s,4s)-4-(hydroxymethyl)cyclohexyloxy)pheny...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225011BDBM50225011(2-(4-((1-benzylpiperidin-3-yl)methoxy)phenyl)-1H-b...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224988BDBM50224988(2-(4-((1-benzoylpiperidin-4-yl)methoxy)phenyl)-1H-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224983BDBM50224983(2-(4-(2-(1-benzylpiperidin-2-yl)ethoxy)phenyl)-1H-...)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225002BDBM50225002(2-(4-(2-(1-benzoylpiperidin-2-yl)ethoxy)phenyl)-1H...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225021BDBM50225021(2-(4-(2-hydroxyethoxy)phenyl)-1H-benzo[d]imidazole...)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224997BDBM50224997(2-(4-(2-(1-(4-chlorobenzyl)piperidin-2-yl)ethoxy)p...)
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225006BDBM50225006(2-(4-((1-(4-methoxybenzyl)piperidin-3-yl)methoxy)p...)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224998BDBM50224998(2-{4-[1-(4-methyl-benzyl)-piperidin-3-ylmethoxy]-p...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224993BDBM50224993(2-(4-((1-(4-chlorobenzyl)piperidin-4-yl)methoxy)ph...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225012BDBM50225012(2-(4-{2-[1-(4-methyl-benzyl)-piperidin-2-yl]-ethox...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225018BDBM50225018(2-(4-((1-(4-methoxybenzyl)piperidin-4-yl)methoxy)p...)
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225019BDBM50225019(2-(4-((1-benzylpiperidin-4-yl)methoxy)phenyl)-1H-b...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224986BDBM50224986(2-{4-[1-(4-methyl-benzyl)-piperidin-4-ylmethoxy]-p...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224981BDBM50224981(2-(4-(3-hydroxycyclopentyloxy)phenyl)-1H-benzo[d]i...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224980BDBM50224980(2-(4-(3-hydroxypropoxy)phenyl)-1H-benzo[d]imidazol...)
Affinity DataIC50: 73nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224994BDBM50224994(2-(4-(2-(1-(4-methoxybenzyl)piperidin-2-yl)ethoxy)...)
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224990BDBM50224990(2-(4-((1-acetylpiperidin-4-yl)methoxy)phenyl)-1H-b...)
Affinity DataIC50: 78nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224992BDBM50224992(2-(4-(4-hydroxycyclohexyloxy)phenyl)-1H-benzo[d]im...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224989BDBM50224989(2-(4-(2-(1-(4-chlorobenzyl)piperidin-4-yl)ethoxy)p...)
Affinity DataIC50: 82nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224995BDBM50224995(2-(4-(2-(1-acetylpiperidin-4-yl)ethoxy)phenyl)-1H-...)
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224996BDBM50224996(2-(4-{2-[1-(4-methyl-benzyl)-piperidin-4-yl]-ethox...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224987BDBM50224987(2-(4-(2-(1-benzylpiperidin-4-yl)ethoxy)phenyl)-1H-...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225020BDBM50225020(2-(4-(2-(1-(4-methoxybenzyl)piperidin-4-yl)ethoxy)...)
Affinity DataIC50: 95nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224991BDBM50224991(2-(4-(1-acetylpiperidin-3-yloxy)phenyl)-1H-benzo[d...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225001BDBM50225001(2-(4-(1-benzylpyrrolidin-3-yloxy)phenyl)-1H-benzo[...)
Affinity DataIC50: 109nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225007BDBM50225007(2-(4-(3-(piperidin-1-yl)propoxy)phenyl)-1H-benzo[d...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225016BDBM50225016(2-(4-(2-(1-(3,4-dichlorobenzyl)piperidin-2-yl)etho...)
Affinity DataIC50: 114nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225015BDBM50225015(2-(4-((1-acetylpiperidin-3-yl)methoxy)phenyl)-1H-b...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224999BDBM50224999(2-(4-(2-(1-(3,4-dichlorobenzyl)piperidin-4-yl)etho...)
Affinity DataIC50: 157nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224985BDBM50224985(2-(4-(piperidin-3-ylmethoxy)phenyl)-1H-benzo[d]imi...)
Affinity DataIC50: 158nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225000BDBM50225000(2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-1H-benzo[d]...)
Affinity DataIC50: 174nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225013BDBM50225013(2-(4-((1-(3,4-dichlorobenzyl)piperidin-4-yl)methox...)
Affinity DataIC50: 176nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225022BDBM50225022(2-(4-(3-(dimethylamino)propoxy)phenyl)-1H-benzo[d]...)
Affinity DataIC50: 176nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224979BDBM50224979(2-(4-(piperidin-3-yloxy)phenyl)-1H-benzo[d]imidazo...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224982BDBM50224982(2-(4-((1-(3,4-dichlorobenzyl)piperidin-3-yl)methox...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225004BDBM50225004(2-(4-(piperidin-4-ylmethoxy)phenyl)-1H-benzo[d]imi...)
Affinity DataIC50: 231nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225003BDBM50225003(2-(4-(1-methylpiperidin-4-yloxy)phenyl)-1H-benzo[d...)
Affinity DataIC50: 233nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50224984BDBM50224984(2-(4-(2-(1-acetylpiperidin-2-yl)ethoxy)phenyl)-1H-...)
Affinity DataIC50: 292nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225009BDBM50225009(2-(4-((1r,4r)-4-(hydroxymethyl)cyclohexyloxy)pheny...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225010BDBM50225010(2-(4-(piperidin-4-yloxy)phenyl)-1H-benzo[d]imidazo...)
Affinity DataIC50: 710nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50225017BDBM50225017(2-(4-(1-methylpyrrolidin-3-yloxy)phenyl)-1H-benzo[...)
Affinity DataIC50: 710nMAssay Description:Inhibition of human recombinant Chk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed