Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50038354
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375331(CHEMBL261253)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375339(CHEMBL258648)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375334(CHEMBL411074)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375337(CHEMBL413828)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375336(CHEMBL411062)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant full length IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375335(CHEMBL260298)
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375330(CHEMBL408712)
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human purified insulin receptor expressed in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375341(CHEMBL261146)
Affinity DataIC50: 77nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50339059(3-cyclobutyl-1-(2-phenylquinolin-7-yl)-imidazo[1,5...)
Affinity DataIC50: 86nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375340(CHEMBL258951)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375332(CHEMBL411082)
Affinity DataIC50: 147nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375333(CHEMBL430051)
Affinity DataIC50: 148nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375338(CHEMBL260888)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM1779(CHEMBL392106 | US8481733, Comparator 2)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50339059(3-cyclobutyl-1-(2-phenylquinolin-7-yl)-imidazo[1,5...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of KDR at 100 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375330(CHEMBL408712)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375340(CHEMBL258951)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of P70S6KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AuroraAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cRafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MAPK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fes/Fps(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FESMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 3(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FYNMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50340953(3-cyclobutyl-1-(quinolin-7-yl)imidazo[1,5-a]pyrazi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50336316(cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phe...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375329(CHEMBL427907)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length IGF1R expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375339(CHEMBL258648)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375336(CHEMBL411062)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375337(CHEMBL413828)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375341(CHEMBL261146)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375335(CHEMBL260298)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50375333(CHEMBL430051)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
Displayed 1 to 50 (of 55 total ) | Next | Last >>
Jump to: