Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50037997
TargetBeta-secretase 1(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226438((S)-5-((S)-1-carboxy-2-phenylethylamino)-4-((S)-2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM16047(EVNXXAEF | N-{(2R,4S,5S)-5-[(L-alpha-glutamyl-L-va...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetEndothiapepsin(Chestnut blight fungus)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226437(2-amino-6-phenethylpyrimidin-4(3H)-one | 2-AMINO-6...)
Affinity DataKd:  2.20E+5nMAssay Description:Binding affinity to endothiapepsin by Biocore ISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226437(2-amino-6-phenethylpyrimidin-4(3H)-one | 2-AMINO-6...)
Affinity DataKd:  6.60E+5nMAssay Description:Binding affinity to BACE1 expressed in HEK293 cells by Biocore ISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50226439(2-amino-6-propylpyrimidin-4(3H)-one | CHEMBL235825)
Affinity DataKd:  4.45E+6nMAssay Description:Binding affinity to BACE1 expressed in HEK293 cells by Biocore ISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)