Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50022069
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231346(1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino...)
Affinity DataIC50:  0.00400nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231377(1-((2R,3S)-4-((cyclopropylmethyl)(3-(4-fluoropheny...)
Affinity DataIC50:  0.00500nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50163634(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  0.0100nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50163634(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  0.0100nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophil at 30 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231350(1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino...)
Affinity DataIC50:  0.0130nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231358(1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl...)
Affinity DataIC50:  0.0380nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231371(1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231360(1-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(propyl)am...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231354(1-((2R,3S)-4-(ethyl((S)-4-(4-fluorophenyl)butan-2-...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231358(1-((2R,3S)-4-((S)-3-(4-fluorobenzyl)piperidin-1-yl...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231379(1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231376(1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231346(1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231347(1-((2R,3S)-3-hydroxy-4-(((1S,2S)-1-hydroxy-1-pheny...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231367(1-((2R,3S)-4-(cyclopropyl(3-(4-fluorophenyl)propyl...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231364(1-((2R,3S)-4-((cyclopropylmethyl)(3-(4-fluoropheny...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231357(1-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(methyl)am...)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231380(1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231361(1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231377(1-((2R,3S)-4-((cyclopropylmethyl)(3-(4-fluoropheny...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231368(1-((1R,2S)-2-(((3-(4-fluorophenyl)propyl)(methyl)a...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231368(1-((1R,2S)-2-(((3-(4-fluorophenyl)propyl)(methyl)a...)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231352(1-((2R,3S)-4-(cyclopropyl(3-(4-fluorophenyl)propyl...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50163634(1-((1R,2S)-2-(((S)-3-(4-fluorobenzyl)piperidin-1-y...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231366(1-((2R,3S)-4-(ethyl((2S,3S)-4-(4-fluorophenyl)-3-h...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231350(1-((2R,3S)-4-(ethyl(3-(4-fluorophenyl)propyl)amino...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231348(1-((2R,3S)-4-(benzyl(3-(4-fluorophenyl)propyl)amin...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231378(1-((2R,3S)-4-(ethyl((S)-4-(4-fluorophenyl)butan-2-...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231359(1-((2R,3S)-4-(cyclohexyl(3-(4-fluorophenyl)propyl)...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231376(1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-...)
Affinity DataIC50:  2.60nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231356(1-((2R,3S)-4-(cyclohexyl(3-(4-fluorophenyl)propyl)...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231373(1-((2R,3S)-4-(ethyl((2S,3R)-4-(4-fluorophenyl)-3-h...)
Affinity DataIC50:  3.40nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231370(1-((1R,2S)-2-((3-(4-fluorophenyl)propylamino)methy...)
Affinity DataIC50:  3.70nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231351(1-((2R,3S)-3-hydroxy-4-(((1R,2S)-1-hydroxy-1-pheny...)
Affinity DataIC50:  5.70nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231374(1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-...)
Affinity DataIC50:  6nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231365(1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-...)
Affinity DataIC50:  9nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231363(1-((2R,3S)-4-(ethyl((2S,3S)-4-(4-fluorophenyl)-3-h...)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231375(1-(3-ethyl-5-(1-methyl-1H-tetrazol-5-yl)phenyl)-3-...)
Affinity DataIC50:  21.6nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231347(1-((2R,3S)-3-hydroxy-4-(((1S,2S)-1-hydroxy-1-pheny...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human CCR3 receptor assessed as inhibition of chemotaxis in eosinophilMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231362(1-((2R,3S)-4-((3-(4-fluorophenyl)propyl)(2,2,2-tri...)
Affinity DataIC50:  59nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231369(1-((1R,2S)-2-(((3-(4-fluorophenyl)propyl)(2,2,2-tr...)
Affinity DataIC50:  60nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231381(1-((2R,3S)-4-(ethyl((2S,3R)-4-(4-fluorophenyl)-3-h...)
Affinity DataIC50:  88nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231355(1-((1R,2S)-3-{adamantan-1-ylmethyl-[3-(4-fluoro-ph...)
Affinity DataIC50:  211nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231372(1-((2R,3S)-3-hydroxy-4-(((1S,2R)-1-hydroxy-1-pheny...)
Affinity DataIC50:  238nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231349(1-((1R,2S)-3-{adamantan-1-ylmethyl-[3-(4-fluoro-ph...)
Affinity DataIC50:  421nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50231353(1-((2R,3S)-3-hydroxy-4-(((1R,2R)-1-hydroxy-1-pheny...)
Affinity DataIC50:  577nMAssay Description:Displacement of [125I] eotaxin from human CCR3 receptor in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed