Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50022073
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231424BDBM50231424((S)-3-(4-(4-(2,6-dicyanophenyl)piperazin-1-yl)phen...)
Affinity DataIC50: 19nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231422BDBM50231422((S)-2-((R)-1-(3,5-dichlorophenylsulfonyl)pyrrolidi...)
Affinity DataIC50: 28nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231417BDBM50231417((S)-4-((1-carboxy-2-(4-(4-phenylpiperazin-1-yl)phe...)
Affinity DataIC50: 42nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231430BDBM50231430((S)-3-(4-(4-(5-acetylthiophen-2-yl)piperazin-1-yl)...)
Affinity DataIC50: 67nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231413BDBM50231413((S)-3-(4-(4-(2-cyanophenyl)piperazin-1-yl)phenyl)-...)
Affinity DataIC50: 67nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231419BDBM50231419((S)-3-(4-(4-(2-nitrophenyl)piperazin-1-yl)phenyl)-...)
Affinity DataIC50: 69nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231412BDBM50231412((S)-3-(4-(4-(pyrazin-2-yl)piperazin-1-yl)phenyl)-2...)
Affinity DataIC50: 75nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231423BDBM50231423((S)-3-(4-(4-phenylpiperazin-1-yl)phenyl)-2-((S)-1-...)
Affinity DataIC50: 76nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231429BDBM50231429((S)-3-(4-(4-(cyclopropanecarbonyl)piperazin-1-yl)p...)
Affinity DataIC50: 80nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231408BDBM50231408((S)-3-(4-(4-(2-cyanophenyl)piperazin-1-yl)phenyl)-...)
Affinity DataIC50: 99nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231421BDBM50231421((S)-3-(4-(4-(4-cyanophenyl)piperazin-1-yl)phenyl)-...)
Affinity DataIC50: 101nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231431BDBM50231431((S)-3-(4-(4-phenylpiperazin-1-yl)phenyl)-2-((S)-1-...)
Affinity DataIC50: 123nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231436BDBM50231436((S)-2-((S)-1-(phenylsulfonyl)pyrrolidine-2-carboxa...)
Affinity DataIC50: 124nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231433BDBM50231433((S)-3-(4-(4-(3-ethoxy-3-oxopropyl)piperazin-1-yl)p...)
Affinity DataIC50: 130nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231434BDBM50231434((S)-3-(4-(4-(2-methoxyphenyl)piperazin-1-yl)phenyl...)
Affinity DataIC50: 135nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231420BDBM50231420((S)-3-(4-(4-(4-nitrophenyl)piperazin-1-yl)phenyl)-...)
Affinity DataIC50: 143nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231409BDBM50231409((S)-3-(4-(4-(4-methoxyphenyl)piperazin-1-yl)phenyl...)
Affinity DataIC50: 152nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231414BDBM50231414((S)-3-(4-(4-(3-methoxyphenyl)piperazin-1-yl)phenyl...)
Affinity DataIC50: 170nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231425BDBM50231425((S)-3-(4-(4-(pyridin-2-yl)piperazin-1-yl)phenyl)-2...)
Affinity DataIC50: 179nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231432BDBM50231432((S)-3-(4-(4-phenylpiperazin-1-yl)phenyl)-2-((S)-3-...)
Affinity DataIC50: 196nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231415BDBM50231415((S)-3-(4-(4-(ethylcarbamoyl)piperazin-1-yl)phenyl)...)
Affinity DataIC50: 200nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231435BDBM50231435((S)-3-(4-(4-benzylpiperazin-1-yl)phenyl)-2-((S)-1-...)
Affinity DataIC50: 222nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231411BDBM50231411((S)-3-(4-(4-methylpiperazin-1-yl)phenyl)-2-((S)-1-...)
Affinity DataIC50: 235nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231410BDBM50231410((S)-3-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)phenyl)...)
Affinity DataIC50: 239nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231406BDBM50231406((S)-3-(4-(4-(2,3-dimethylphenyl)piperazin-1-yl)phe...)
Affinity DataIC50: 327nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231418BDBM50231418((S)-3-(4-(4-p-tolylpiperazin-1-yl)phenyl)-2-((S)-1...)
Affinity DataIC50: 353nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231428BDBM50231428((S)-3-[4-(4-biphenyl-4-yl-piperazin-1-yl)-phenyl]-...)
Affinity DataIC50: 450nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231407BDBM50231407((S)-2-(3,5-dichloroisonicotinamido)-3-(4-(4-phenyl...)
Affinity DataIC50: 510nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231416BDBM50231416((S)-2-(2,6-dichlorobenzamido)-3-(4-(4-phenylpipera...)
Affinity DataIC50: 1.12E+3nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231426BDBM50231426((S)-2-(2-fluoro-6-(trifluoromethyl)benzamido)-3-(4...)
Affinity DataIC50: 4.32E+3nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetIntegrin alpha-4(Human)
Kyowa Hakko Kogyo

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231427BDBM50231427((S)-2-(2,6-difluorobenzamido)-3-(4-(4-phenylpipera...)
Affinity DataIC50: 6.81E+3nMAssay Description:Displacement of VCAM1 from human VLA4 in Jurkat cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed