Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50022100
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231610BDBM50231610((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(4...)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231619BDBM50231619((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(2-hy...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 receptor in human monocytes assessed as inhibition of MCP1-mediated chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231615BDBM50231615(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at CCR2 receptor in human monocytes assessed as inhibition of MCP1-mediated chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231620BDBM50231620((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(4...)
Affinity DataIC50: 3nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231613BDBM50231613(N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(3-fluorop...)
Affinity DataIC50: 4nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231615BDBM50231615(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231615BDBM50231615(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231614BDBM50231614(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231612BDBM50231612(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231611BDBM50231611(N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(3-hydroxy...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231619BDBM50231619((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(2-hy...)
Affinity DataIC50: 6nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231620BDBM50231620((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(4...)
Affinity DataIC50: 16nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231618BDBM50231618(N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(6-chlorop...)
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231617BDBM50231617(3-(1-(3-((3,5-bis(trifluoromethyl)benzyl)carbamoyl...)
Affinity DataIC50: 41nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231617BDBM50231617(3-(1-(3-((3,5-bis(trifluoromethyl)benzyl)carbamoyl...)
Affinity DataIC50: 41nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231621BDBM50231621(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 44nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231608BDBM50231608(3-(1-(3-((3,5-bis(trifluoromethyl)benzyl)carbamoyl...)
Affinity DataIC50: 45nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231613BDBM50231613(N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(3-fluorop...)
Affinity DataIC50: 45nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231622BDBM50231622(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 50nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231610BDBM50231610((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(4...)
Affinity DataIC50: 54nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231616BDBM50231616(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 64nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231611BDBM50231611(N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(3-hydroxy...)
Affinity DataIC50: 67nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231621BDBM50231621(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 130nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231609BDBM50231609(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 144nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231623BDBM50231623(N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(6-chlorop...)
Affinity DataIC50: 165nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor in human monocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231618BDBM50231618(N-(3,5-bis(trifluoromethyl)benzyl)-3-(4-(6-chlorop...)
Affinity DataIC50: 186nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231614BDBM50231614(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 217nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231612BDBM50231612(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 224nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231617BDBM50231617(3-(1-(3-((3,5-bis(trifluoromethyl)benzyl)carbamoyl...)
Affinity DataIC50: 600nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231617BDBM50231617(3-(1-(3-((3,5-bis(trifluoromethyl)benzyl)carbamoyl...)
Affinity DataIC50: 600nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231619BDBM50231619((1S,3R)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(2-hy...)
Affinity DataIC50: 844nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231615BDBM50231615(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231615BDBM50231615(N-(3,5-bis(trifluoromethyl)benzyl)-1-isopropyl-3-(...)
Affinity DataIC50: 1.80E+3nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50231608BDBM50231608(3-(1-(3-((3,5-bis(trifluoromethyl)benzyl)carbamoyl...)
Affinity DataIC50: 1.97E+4nMAssay Description:Displacement of [33S]MK499 from human ERG expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed