Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50038256
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373826BDBM50373826(CHEMBL256470)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373827BDBM50373827(CHEMBL270865)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373831BDBM50373831(CHEMBL272087)
Affinity DataIC50: 40nMAssay Description:Antagonist activity at LPA3 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373818BDBM50373818(CHEMBL404575)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at LPA1 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373815BDBM50373815(CHEMBL401756)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373817BDBM50373817(CHEMBL404452)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373828BDBM50373828(CHEMBL427893)
Affinity DataIC50: 310nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373829BDBM50373829(CHEMBL429681)
Affinity DataIC50: 730nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373821BDBM50373821(CHEMBL401747)
Affinity DataIC50: 730nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373814BDBM50373814(CHEMBL270877)
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373819BDBM50373819(CHEMBL402218)
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at LPA2 assessed as inhibition of LPA-induced Ca2+ fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373830BDBM50373830(CHEMBL401543)
Affinity DataIC50: 1.86E+3nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373820BDBM50373820(CHEMBL270878)
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373816BDBM50373816(CHEMBL270237)
Affinity DataIC50: 6.61E+3nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373818BDBM50373818(CHEMBL404575)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at LPA3 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373824BDBM50373824(CHEMBL272352)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373825BDBM50373825(CHEMBL256478)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373822BDBM50373822(CHEMBL257899)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373823BDBM50373823(CHEMBL406676)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373831BDBM50373831(CHEMBL272087)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373817BDBM50373817(CHEMBL404452)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at LPA1 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373818BDBM50373818(CHEMBL404575)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at LPA2 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373817BDBM50373817(CHEMBL404452)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at LPA3 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373826BDBM50373826(CHEMBL256470)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at LPA1 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 1(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373831BDBM50373831(CHEMBL272087)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at LPA1 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 3(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50373826BDBM50373826(CHEMBL256470)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at LPA3 expressed in RH7777 cells with Gi4-protein and aequorin by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed