Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50022150
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231938((2,5-dimethyloxazol-4-yl)methyl (R)-1-((4S,5S,7R)-...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231937(N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)...)
Affinity DataIC50: 1nMAssay Description:Inhibition of memapsin 2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM16047(EVNXXAEF | N-{(2R,4S,5S)-5-[(L-alpha-glutamyl-L-va...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231937(N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231932(N1-((2S,3R)-3-hydroxy-4-((1-(methylsulfonyl)-1H-in...)
Affinity DataKi:  27nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231932(N1-((2S,3R)-3-hydroxy-4-((1-(methylsulfonyl)-1H-in...)
Affinity DataIC50: 200nMAssay Description:Inhibition of memapsin 2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231933(N1-((2S,3R)-4-((1H-indol-6-yl)methylamino)-3-hydro...)
Affinity DataKi:  230nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231941(N1-((2S,3R)-3-hydroxy-4-(isopropylamino)-1-phenylb...)
Affinity DataKi:  425nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231931(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataKi:  552nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231940(N1-((2S,3R)-3-hydroxy-4-((S)-1-(isopropylamino)-3-...)
Affinity DataKi:  564nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231934(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataKi:  617nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231933(N1-((2S,3R)-4-((1H-indol-6-yl)methylamino)-3-hydro...)
Affinity DataIC50: 620nMAssay Description:Inhibition of memapsin 2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231937(N-{(1S,2R)-1-benzyl-2-hydroxy-3-[(3-methoxybenzyl)...)
Affinity DataIC50: 696nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231939(N1-((2S,3R)-4-(3-methoxybenzylamino)-3-hydroxy-1-p...)
Affinity DataKi:  894nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231936(N1-((2R,3S)-1-(3-methoxybenzylamino)-2-hydroxy-5-m...)
Affinity DataKi:  916nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231941(N1-((2S,3R)-3-hydroxy-4-(isopropylamino)-1-phenylb...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of memapsin 2 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50231935((2,5-dimethyloxazol-4-yl)methyl (R)-1-((2S,3R)-4-(...)
Affinity DataKi:  1.50E+4nMAssay Description:Binding affinity to recombinant memapsin 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed