Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50022210
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232653(N-(2-aminophenyl)-4-((6-methoxybenzo[d]thiazol-2-y...)
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232646(N-(2-aminophenyl)-4-((6-bromobenzo[d]thiazol-2-yla...)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232650(N-(2-aminophenyl)-4-((6-(2-morpholinoethoxy)benzo[...)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232648(N-(2-aminophenyl)-4-((6-methoxy-1H-benzo[d]imidazo...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232649(N-(2-aminophenyl)-4-((6-(pyridin-2-ylmethylamino)b...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232656(N-(2-aminophenyl)-4-((5-phenyl-1H-pyrazol-3-ylamin...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232658(N-(2-aminophenyl)-4-((6-(2-morpholinoethylamino)be...)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232660(N-(2-aminophenyl)-4-((5-phenyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232655(4-((1H-benzo[d]imidazol-2-ylthio)methyl)-N-(2-amin...)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232651(N-(2-aminophenyl)-4-((benzo[d]thiazol-2-ylthio)met...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232647(N-(2-aminophenyl)-4-((5-chlorobenzo[d]oxazol-2-yla...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232652(4-((1H-benzo[d]imidazol-2-ylamino)methyl)-N-(2-ami...)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232662(N-(2-aminophenyl)-4-((5-(methylthio)-1H-1,2,4-tria...)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232661(N-(2-aminophenyl)-4-((5-(4-chlorophenyl)thiazol-2-...)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232645(N-(2-aminophenyl)-4-((5-bromothiazol-2-ylamino)met...)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232657(4-((1H-imidazol-2-ylthio)methyl)-N-(2-aminophenyl)...)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232654(N-(2-aminophenyl)-4-((6-(pyridin-3-ylmethylamino)b...)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232652(4-((1H-benzo[d]imidazol-2-ylamino)methyl)-N-(2-ami...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232647(N-(2-aminophenyl)-4-((5-chlorobenzo[d]oxazol-2-yla...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232659(N-(2-aminophenyl)-4-((1-methyl-1H-imidazol-2-ylthi...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant HDAC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232648(N-(2-aminophenyl)-4-((6-methoxy-1H-benzo[d]imidazo...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232653(N-(2-aminophenyl)-4-((6-methoxybenzo[d]thiazol-2-y...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232650(N-(2-aminophenyl)-4-((6-(2-morpholinoethoxy)benzo[...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232654(N-(2-aminophenyl)-4-((6-(pyridin-3-ylmethylamino)b...)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232646(N-(2-aminophenyl)-4-((6-bromobenzo[d]thiazol-2-yla...)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232649(N-(2-aminophenyl)-4-((6-(pyridin-2-ylmethylamino)b...)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232651(N-(2-aminophenyl)-4-((benzo[d]thiazol-2-ylthio)met...)
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Methylgene

Curated by ChEMBL
LigandPNGBDBM50232658(N-(2-aminophenyl)-4-((6-(2-morpholinoethylamino)be...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of HDAC1 in human T24 cells assessed as induction of histone H4 acetylation after 16 hrs relative to MS-275More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2009
Entry Details Article
PubMed