Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 50022359
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM28798((2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)pheny...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234375((S)-2-ethoxy-3-(4-(2-(6-((methoxyimino)(phenyl)met...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234377(2-ethoxy-3-(4-(2-(6-((methoxyimino)(phenyl)methyl)...)
Affinity DataKi:  48nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234372((R)-2-ethoxy-3-(4-(2-(6-((methoxyimino)(phenyl)met...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234373(CHEMBL253851 | ethyl 2-ethoxy-3-(4-(2-(6-((hydroxy...)
Affinity DataKi:  618nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234374((S)-ethyl 2-ethoxy-3-(4-(2-(6-((methoxyimino)(phen...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234378(CHEMBL399629 | ethyl 2-ethoxy-3-(4-(2-(6-((methoxy...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234379(CHEMBL252995 | dimethyl 2-(4-(2-(6-benzoyl-4,4-dim...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234376(CHEMBL252996 | dimethyl 2-(4-(2-(6-((hydroxyimino)...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]Rosiglitazone from human PPARgammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234372((R)-2-ethoxy-3-(4-(2-(6-((methoxyimino)(phenyl)met...)
Affinity DataEC50:  194nMAssay Description:Agonist activity at human PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234378(CHEMBL399629 | ethyl 2-ethoxy-3-(4-(2-(6-((methoxy...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at human PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234376(CHEMBL252996 | dimethyl 2-(4-(2-(6-((hydroxyimino)...)
Affinity DataEC50:  195nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234377(2-ethoxy-3-(4-(2-(6-((methoxyimino)(phenyl)methyl)...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234379(CHEMBL252995 | dimethyl 2-(4-(2-(6-benzoyl-4,4-dim...)
Affinity DataEC50:  152nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234373(CHEMBL253851 | ethyl 2-ethoxy-3-(4-(2-(6-((hydroxy...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234374((S)-ethyl 2-ethoxy-3-(4-(2-(6-((methoxyimino)(phen...)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234374((S)-ethyl 2-ethoxy-3-(4-(2-(6-((methoxyimino)(phen...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234372((R)-2-ethoxy-3-(4-(2-(6-((methoxyimino)(phenyl)met...)
Affinity DataEC50:  65nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234375((S)-2-ethoxy-3-(4-(2-(6-((methoxyimino)(phenyl)met...)
Affinity DataEC50:  114nMAssay Description:Agonist activity at human PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM28798((2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)pheny...)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234377(2-ethoxy-3-(4-(2-(6-((methoxyimino)(phenyl)methyl)...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234375((S)-2-ethoxy-3-(4-(2-(6-((methoxyimino)(phenyl)met...)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM28798((2S)-2-ethoxy-3-(4-{2-[4-(methanesulfonyloxy)pheny...)
Affinity DataEC50:  414nMAssay Description:Agonist activity at human PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234373(CHEMBL253851 | ethyl 2-ethoxy-3-(4-(2-(6-((hydroxy...)
Affinity DataEC50:  189nMAssay Description:Agonist activity at human PPARalpha by GAL4 transactivation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Spot-Ea3857

Curated by ChEMBL
LigandPNGBDBM50234378(CHEMBL399629 | ethyl 2-ethoxy-3-(4-(2-(6-((methoxy...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at human PPARalpha at 100 uM by GAL4 transactivation assay relative to WY 14,643More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed