Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 2466
LigandPNGBDBM20954(2-(4-methoxy-2,6-dimethylphenoxy)-3,6-dimethyl-4-(...)
Affinity DataIC50: 2nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20950(2-(4-bromo-2,6-dimethylphenoxy)-3,6-dimethyl-4-(pe...)
Affinity DataIC50: 2.60nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20959(2-[4-(methoxymethyl)-2,6-dimethylphenoxy]-3,6-dime...)
Affinity DataIC50: 3.20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20949(2-(4-chloro-2,6-dimethylphenoxy)-3,6-dimethyl-4-(p...)
Affinity DataIC50: 5.5nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20933(JMC511377 Compound 2 | 3,6-dimethyl-4-(pentan-3-yl...)
Affinity DataIC50: 6.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20935(3-ethyl-6-methyl-4-(pentan-3-yloxy)-2-(2,4,6-trime...)
Affinity DataIC50: 9.10nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20941(3-bromo-6-methyl-4-(pentan-3-yloxy)-2-(2,4,6-trime...)
Affinity DataIC50: 9.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20947(2-(2,6-dimethyl-4-propylphenoxy)-3,6-dimethyl-4-(p...)
Affinity DataIC50: 9.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20965(3,6-dimethyl-4-(pentan-3-yloxy)-2-[(2,4,6-trimethy...)
Affinity DataIC50: 10nMAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20946(2-(4-ethyl-2,6-dimethylphenoxy)-3,6-dimethyl-4-(pe...)
Affinity DataIC50: 11nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20962(4-[(1-methoxybutan-2-yl)oxy]-3,6-dimethyl-2-(2,4,6...)
Affinity DataIC50: 11nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20951(2-(4-iodo-2,6-dimethylphenoxy)-3,6-dimethyl-4-(pen...)
Affinity DataIC50: 12nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20939(6-methyl-4-(pentan-3-yloxy)-2-(2,4,6-trimethylphen...)
Affinity DataIC50: 12nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20938(6-methyl-3-nitro-4-(pentan-3-yloxy)-2-(2,4,6-trime...)
Affinity DataIC50: 15nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20964(3,6-dimethyl-4-[(2E)-pent-2-en-3-yloxy]-2-(2,4,6-t...)
Affinity DataIC50: 16nMAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20952(4-{[3,6-dimethyl-4-(pentan-3-yloxy)pyridin-2-yl]ox...)
Affinity DataIC50: 18nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20955(2-(4-ethoxy-2,6-dimethylphenoxy)-3,6-dimethyl-4-(p...)
Affinity DataIC50: 20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20940(N,N,6-trimethyl-4-(pentan-3-yloxy)-2-(2,4,6-trimet...)
Affinity DataIC50: 25nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20961(4-(butan-2-yloxy)-3,6-dimethyl-2-(2,4,6-trimethylp...)
Affinity DataIC50: 28nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20948(2-(4-fluoro-2,6-dimethylphenoxy)-3,6-dimethyl-4-(p...)
Affinity DataIC50: 32nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20957(4-{[3,6-dimethyl-4-(pentan-3-yloxy)pyridin-2-yl]ox...)
Affinity DataIC50: 40nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20960(2-(4-{[3,6-dimethyl-4-(pentan-3-yloxy)pyridin-2-yl...)
Affinity DataIC50: 40nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20958((4-{[3,6-dimethyl-4-(pentan-3-yloxy)pyridin-2-yl]o...)
Affinity DataIC50: 61nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20934(6-ethyl-3-methyl-4-(pentan-3-yloxy)-2-(2,4,6-trime...)
Affinity DataIC50: 86nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20963(3,6-Dimethyl-4-(tetrahydro-furan-3-yloxy)-2-(2,4,6...)
Affinity DataIC50: 100nMAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20956(2-[2,6-dimethyl-4-(propan-2-yloxy)phenoxy]-3,6-dim...)
Affinity DataIC50: 110nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20945(2-(2,6-dimethylphenoxy)-3,6-dimethyl-4-(pentan-3-y...)
Affinity DataIC50: 110nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20936(2-methyl-4-(pentan-3-yloxy)-6-(2,4,6-trimethylphen...)
Affinity DataIC50: 150nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20943(2,3,5-trimethyl-4-(pentan-3-yloxy)-6-(2,4,6-trimet...)
Affinity DataIC50: 180nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20937(methyl 6-methyl-4-(pentan-3-yloxy)-2-(2,4,6-trimet...)
Affinity DataIC50: 470nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20953(4-{[3,6-dimethyl-4-(pentan-3-yloxy)pyridin-2-yl]ox...)
Affinity DataIC50: 1.40E+3nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20942(6-methyl-4-(pentan-3-yloxy)-2-(2,4,6-trimethylphen...)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed
LigandPNGBDBM20944(3-ethyl-2,5-dimethyl-4-(pentan-3-yloxy)-6-(2,4,6-t...)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2008
Entry Details Article
PubMed