Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50025810
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50095155(CHEMBL316446 | (S)-1-[(S)-2-Amino-3-(4-hydroxy-phe...)
Affinity DataKi:  1.45nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50080456(2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)
Affinity DataKi:  11.4nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261483(YGGWL-NH2 | CHEMBL504973)
Affinity DataKi:  12.1nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50080456(2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)
Affinity DataIC50: 26.1nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261483(YGGWL-NH2 | CHEMBL504973)
Affinity DataIC50: 27.5nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261526(Ac-YGGFL-NH2 | CHEMBL500212)
Affinity DataKi:  37.3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261483(YGGWL-NH2 | CHEMBL504973)
Affinity DataIC50: 49.2nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50080456(2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-p...)
Affinity DataIC50: 57.8nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261480(YPWA-NH2 | CHEMBL512955)
Affinity DataKi:  72.7nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261527(YGWFL-NH2 | CHEMBL455502)
Affinity DataKi:  113nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261527(YGWFL-NH2 | CHEMBL455502)
Affinity DataIC50: 126nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261527(YGWFL-NH2 | CHEMBL455502)
Affinity DataIC50: 132nMAssay Description:Agonist activity at mu opioid receptor assessed as inhibition of forskolin-induced cAMP production in human SH-SY5Y cells pretreated for 24 hrs with ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50209313(H-Tyr-Pro-Ala-Phe-NH2 | YPAF-NH2 | (S)-N-((S)-1-((...)
Affinity DataKi:  226nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261482(YPAA-NH2 | CHEMBL466147)
Affinity DataKi:  705nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50261481(YAWF-NH2 | CHEMBL445690)
Affinity DataKi:  3.19E+3nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in human SH-SY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed