Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 2848
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25248BDBM25248(N-(2-aminophenyl)-4-[5-(piperidin-1-ylmethyl)-1,3-...)
Affinity DataIC50: 22nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25250BDBM25250(N-(2-aminophenyl)-4-{5-[(propylamino)methyl]-1,3-t...)
Affinity DataIC50: 28nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25255BDBM25255(N-(2-aminophenyl)-4-(1-{[4-(methylcarbamoyl)phenyl...)
Affinity DataIC50: 31nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25254BDBM25254(N-(2-aminophenyl)-4-(1-{[4-(ethylcarbamoyl)phenyl]...)
Affinity DataIC50: 35nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25249BDBM25249(N-(2-aminophenyl)-4-{5-[(ethylamino)methyl]-1,3-th...)
Affinity DataIC50: 38nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25247BDBM25247(N-(2-aminophenyl)-4-(1-benzylpiperidin-4-yl)benzam...)
Affinity DataIC50: 45nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25253BDBM25253(N-(2-aminophenyl)-4-(1-{[4-(cyclopropylcarbamoyl)p...)
Affinity DataIC50: 58nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25251BDBM25251(N-(2-aminophenyl)-4-(1-{2-[(2-fluorophenyl)carbamo...)
Affinity DataIC50: 68nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25252BDBM25252(N-(2-aminophenyl)-4-(1-{[4-(dimethylcarbamoyl)phen...)
Affinity DataIC50: 85nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25245BDBM25245(N-(2-aminophenyl)-4-(1,3-thiazol-2-yl)benzamide | ...)
Affinity DataIC50: 123nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25246BDBM25246(N-(2-aminophenyl)-4-(1-methylpiperidin-4-yl)benzam...)
Affinity DataIC50: 138nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Astrazeneca

LigandChemical structure of BindingDB Monomer ID 25244BDBM25244(N-(2-aminophenyl)pyridine-2-carboxamide | benzamid...)
Affinity DataIC50: 2.46E+3nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed