Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50038521
TargetUrotensin-2 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412075(CHEMBL404177)
Affinity DataKd:  10nMAssay Description:Antagonist activity at human urotensin 2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetUrotensin-2 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241425(2-((3,4-dichlorophenyl)(methyl)amino)-1-(2-(pyrrol...)
Affinity DataIC50: 631nMAssay Description:Inhibition of human recombinant urotensin 2 receptor-mediated calcium mobilization expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50239135(2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3...)
Affinity DataIC50: 800nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50239135(2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed