Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50038521
TargetUrotensin-2 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50241425(2-((3,4-dichlorophenyl)(methyl)amino)-1-(2-(pyrrol...)
Affinity DataIC50:  631nMAssay Description:Inhibition of human recombinant urotensin 2 receptor-mediated calcium mobilization expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50239135(2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3...)
Affinity DataIC50:  800nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50239135(2-((3,4-dichlorophenyl)(methyl)amino)-1-((2R,3R)-3...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrotensin-2 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50412075(CHEMBL404177)
Affinity DataKd:  10nMAssay Description:Antagonist activity at human urotensin 2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed