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Found 12 Enz. Inhib. hit(s) with all data for entry = 50000706
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007355((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-methyl-1...)
Affinity DataIC50:  6.30nMAssay Description:Compound was evaluated for the Opioid receptor kappa 1 affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007344((S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2...)
Affinity DataIC50:  6.90nMAssay Description:Compound was evaluated for the Opioid receptor kappa 1 affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008845(2-(3,4-Dichloro-phenyl)-N-(2,2-dimethyl-1-pyrrolid...)
Affinity DataIC50:  24nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50007361(2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-methyl-2-pyr...)
Affinity DataIC50:  53nMAssay Description:Compound was evaluated for the Opioid receptor kappa 1 affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008843(2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-methyl-2-pyr...)
Affinity DataIC50:  85nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50:  96nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008847(2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataIC50:  1.54E+3nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008846(2-(3,4-Dichloro-phenyl)-N-(1,1-dimethyl-2-pyrrolid...)
Affinity DataIC50:  2.06E+3nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)
Affinity DataIC50:  2.39E+3nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008844(2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-methyl-2-pyr...)
Affinity DataIC50:  3.41E+3nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008850(2-(3,4-Dichloro-phenyl)-N-methyl-N-(2-pyrrolidin-1...)
Affinity DataIC50:  6.12E+3nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Ici Pharmaceuticals Group

Curated by ChEMBL
LigandPNGBDBM50008849(2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-methyl-2-pyr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound was evaluated for the opioid receptor kappa affinity using guinea pig brain membranes.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed