Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50035902
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008856(CHEMBL544276 | 2-Methyl-acenaphthene-1-carboxylic ...)
Affinity DataKi:  0.370nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008858(CHEMBL539246 | 2-Benzofuran-4-yl-N-methyl-N-(7-pyr...)
Affinity DataKi:  0.830nMAssay Description:Compound was evaluated for Opioid receptor kappa 1 affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008852(CHEMBL543809 | 2-Methyl-acenaphthene-1-carboxylic ...)
Affinity DataKi:  1.20nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008857(CHEMBL543329 | N-Methyl-2-naphthalen-1-yl-N-(7-pyr...)
Affinity DataKi:  3.40nMAssay Description:Compound was evaluated for Opioid receptor kappa 1 affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008854(CHEMBL543331 | 2-Benzo[b]thiophen-4-yl-N-methyl-N-...)
Affinity DataKi:  3.70nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  10nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008855(CHEMBL300831 | 4,5-Dihydro-3H-naphtho[1,8-bc]thiop...)
Affinity DataKi:  11nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008855(CHEMBL300831 | 4,5-Dihydro-3H-naphtho[1,8-bc]thiop...)
Affinity DataKi:  11.1nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008855(CHEMBL300831 | 4,5-Dihydro-3H-naphtho[1,8-bc]thiop...)
Affinity DataKi:  62nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008855(CHEMBL300831 | 4,5-Dihydro-3H-naphtho[1,8-bc]thiop...)
Affinity DataKi:  62nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008853(CHEMBL300832 | 2-Bromo-4,5-dihydro-3H-naphtho[1,8-...)
Affinity DataKi:  170nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008853(CHEMBL300832 | 2-Bromo-4,5-dihydro-3H-naphtho[1,8-...)
Affinity DataKi:  170nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008851(CHEMBL553114 | 2-Benzo[b]thiophen-4-yl-N-methyl-N-...)
Affinity DataKi:  172nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008851(CHEMBL553114 | 2-Benzo[b]thiophen-4-yl-N-methyl-N-...)
Affinity DataKi:  172nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008851(CHEMBL553114 | 2-Benzo[b]thiophen-4-yl-N-methyl-N-...)
Affinity DataKi:  176nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008856(CHEMBL544276 | 2-Methyl-acenaphthene-1-carboxylic ...)
Affinity DataKi:  244nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008853(CHEMBL300832 | 2-Bromo-4,5-dihydro-3H-naphtho[1,8-...)
Affinity DataKi:  272nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008853(CHEMBL300832 | 2-Bromo-4,5-dihydro-3H-naphtho[1,8-...)
Affinity DataKi:  272nMAssay Description:Opioid receptor kappa affinity, determined with [3H]etorphine in the presence of excess unlabeled [D-Ala2-MePhe4-Glyol5]-enkephalinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008852(CHEMBL543809 | 2-Methyl-acenaphthene-1-carboxylic ...)
Affinity DataKi:  273nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008854(CHEMBL543331 | 2-Benzo[b]thiophen-4-yl-N-methyl-N-...)
Affinity DataKi:  410nMAssay Description:Compound was evaluated for the Opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008856(CHEMBL544276 | 2-Methyl-acenaphthene-1-carboxylic ...)
Affinity DataKi:  578nMAssay Description:Compound was evaluated for the opioid receptor delta affinityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008857(CHEMBL543329 | N-Methyl-2-naphthalen-1-yl-N-(7-pyr...)
Affinity DataKi:  864nMAssay Description:Compound was evaluated for the Opioid receptor mu 1 affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataKi:  880nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008851(CHEMBL553114 | 2-Benzo[b]thiophen-4-yl-N-methyl-N-...)
Affinity DataKi: >1.00E+3nMAssay Description:Compound was evaluated for the opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008858(CHEMBL539246 | 2-Benzofuran-4-yl-N-methyl-N-(7-pyr...)
Affinity DataKi:  1.26E+3nMAssay Description:Compound was evaluated for the Opioid receptor mu 1 affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Parke-Davis Research Unit

Curated by ChEMBL
LigandPNGBDBM50008851(CHEMBL553114 | 2-Benzo[b]thiophen-4-yl-N-methyl-N-...)
Affinity DataKi:  2.46E+3nMAssay Description:Compound was evaluated for the Opioid receptor mu affinity determined with [3H][D-Ala2-MePhe4-Gly-ol5]-enkephalin (DAGOL) in the presence of excess u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed