Compile Data Set for Download or QSAR
Report error Found 244 Enz. Inhib. hit(s) with all data for entry = 50004135
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: 975nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of recombinant ARK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479261(Altertoxin I)
Affinity DataIC50: 1.87E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of recombinant B-RAF-V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of recombinant ARK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 2.22E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of recombinant CDK2/CycAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479261(Altertoxin I)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 2.87E+3nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 3.15E+3nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50276157(CHEMBL483526 | Alternariol 5-O-Methyl Ether)
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.56E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50276157(CHEMBL483526 | Alternariol 5-O-Methyl Ether)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.67E+3nMAssay Description:Inhibition of recombinant ARK5More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.71E+3nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 3.78E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 3.81E+3nMAssay Description:Inhibition of recombinant EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 3.81E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of recombinant PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of recombinant Aurora B phosphorylation in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of recombinant FLT3 phosphorylation transfected in mouse embryonic fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of recombinant VEGFR2 phosphorylation in human HUE cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of recombinant IGF1R phosphorylation transfected in mouse embryonic fibroblastMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479261(Altertoxin I)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50276157(CHEMBL483526 | Alternariol 5-O-Methyl Ether)
Affinity DataIC50: 4.04E+3nMAssay Description:Inhibition of recombinant VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50276157(CHEMBL483526 | Alternariol 5-O-Methyl Ether)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant INSRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50276157(CHEMBL483526 | Alternariol 5-O-Methyl Ether)
Affinity DataIC50: 4.77E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479261(Altertoxin I)
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of recombinant SAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479261(Altertoxin I)
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of recombinant IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479261(Altertoxin I)
Affinity DataIC50: 4.82E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 4.85E+3nMAssay Description:Inhibition of recombinant SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 4.85E+3nMAssay Description:Inhibition of recombinant TIE2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479264(Alternariol 5-O-Sulfate | CHEMBL483525)
Affinity DataIC50: 5.02E+3nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479267(CHEBI:64983 | Alternariol)
Affinity DataIC50: 5.03E+3nMAssay Description:Inhibition of recombinant VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetEphrin type-B receptor 4(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50276157(CHEMBL483526 | Alternariol 5-O-Methyl Ether)
Affinity DataIC50: 5.14E+3nMAssay Description:Inhibition of recombinant EPHB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant B-RAF-V600E mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479266(CHEMBL520144)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of recombinant Aurora AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50479263(Desmethylaltenusin)
Affinity DataIC50: 5.43E+3nMAssay Description:Inhibition of recombinant Aurora BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Heinrich-Heine-Universit£T

Curated by ChEMBL
LigandPNGBDBM50576(4-methoxy-2-[2-methyl-4,5-bis(oxidanyl)phenyl]-6-o...)
Affinity DataIC50: 5.51E+3nMAssay Description:Inhibition of recombinant FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
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