Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 3075
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27542BDBM27542(4-(3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H...)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27662BDBM27662(4-[(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]carbo...)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27661BDBM27661(4-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27680BDBM27680(2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27681BDBM27681(5-fluoro-2-[(4-fluoro-3-{[4-(2-phenoxypropanoyl)pi...)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27663BDBM27663(2-{[3-(piperazin-1-ylcarbonyl)phenyl]methoxy}benza...)
Affinity DataIC50: 18nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27674BDBM27674(2-[2-(4-fluoro-3-{[4-(2-phenoxypropanoyl)piperazin...)
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27666BDBM27666(2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 24nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27675BDBM27675(5-fluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbonyl)ph...)
Affinity DataIC50: 29nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27667BDBM27667(2-[(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]carbo...)
Affinity DataIC50: 36nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27668BDBM27668(2-[(4-fluoro-3-{[4-(2-phenoxypropanoyl)piperazin-1...)
Affinity DataIC50: 50nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27664BDBM27664(2-{[4-fluoro-3-(piperazin-1-ylcarbonyl)phenyl]meth...)
Affinity DataIC50: 61nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27672BDBM27672(2-(2-{3-[(4-cyclopentanecarbonylpiperazin-1-yl)car...)
Affinity DataIC50: 103nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27665BDBM27665(2-({3-[(4-cyclopentanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 188nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27673BDBM27673(2-[2-(3-{[4-(2-phenoxypropanoyl)piperazin-1-yl]car...)
Affinity DataIC50: 200nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27671BDBM27671(2-(2-{3-[(4-cyclopentanecarbonylpiperazin-1-yl)car...)
Affinity DataIC50: 200nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27676BDBM27676(4,5-difluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbony...)
Affinity DataIC50: 240nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27677BDBM27677(4-fluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbonyl)ph...)
Affinity DataIC50: 250nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27660BDBM27660(CHEMBL66761 | 4-benzyl-1,2-dihydrophthalazin-1-one...)
Affinity DataIC50: 770nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27669BDBM27669(2-{2-[3-(piperazin-1-ylcarbonyl)phenyl]ethoxy}benz...)
Affinity DataIC50: 970nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27678BDBM27678(3,5-difluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbony...)
Affinity DataIC50: 1.50E+3nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27679BDBM27679(3,6-difluoro-2-{[4-fluoro-3-(piperazin-1-ylcarbony...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Kudos Pharmaceuticals

LigandChemical structure of BindingDB Monomer ID 27670BDBM27670(2-{2-[4-fluoro-3-(piperazin-1-ylcarbonyl)phenyl]et...)
Affinity DataIC50: 1.00E+4nMpH: 7.4 T: 2°CAssay Description:A FlashPlate scintillation proximity assay has been developed to identify inhibitors of PARP-1. The mechanism of action of the assay requires the bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2009
Entry Details Article
PubMed