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Found 25 Enz. Inhib. hit(s) with all data for entry = 50026494
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251821(3-ethyl-6-(phenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251762(6-(3-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251729(6-(2-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataKi:  14nMAssay Description:Inhibition of 5HT2C (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251692(6-(4-chlorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251729(6-(2-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251690(6-(2-chlorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251763(6-(3-methoxyphenylsulfonyl)-3-methyl-1,2,3,4,5,6-h...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251689(6-(4-fluorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251728(6-(5-chloronaphthalen-2-ylsulfonyl)-1,2,3,4,5,6-he...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251694(6-tosyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole ...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251654(6-(3-fluorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251730(6-(4-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251691(6-(3-chlorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251727(6-(4-(trifluoromethyl)phenylsulfonyl)-1,2,3,4,5,6-...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251764(3-ethyl-6-(3-methoxyphenylsulfonyl)-1,2,3,4,5,6-he...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251693(6-(m-tolylsulfonyl)-1,2,3,4,5,6-hexahydroazepino[4...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251766(3-isopropyl-6-(3-methoxyphenylsulfonyl)-1,2,3,4,5,...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251726(6-(3-(trifluoromethyl)phenylsulfonyl)-1,2,3,4,5,6-...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251765(6-(3-methoxyphenylsulfonyl)-3-propyl-1,2,3,4,5,6-h...)
Affinity DataKi:  124nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251790(3-benzyl-6-(3-methoxyphenylsulfonyl)-1,2,3,4,5,6-h...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251653(6-(phenylsulfonyl)-1,2,3,4,5,6-hexahydroazepino[4,...)
Affinity DataKi:  193nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251793(3-cyclohexyl-6-(3-methoxyphenylsulfonyl)-1,2,3,4,5...)
Affinity DataKi:  253nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251792(3-cyclopentyl-6-(3-methoxyphenylsulfonyl)-1,2,3,4,...)
Affinity DataKi:  324nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251791(6-(3-methoxyphenylsulfonyl)-3-phenethyl-1,2,3,4,5,...)
Affinity DataKi:  504nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50251729(6-(2-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataIC50:  162nMAssay Description:Antagonist activity at cloned human 5HT6 receptor expressed in HeLa cells assessed as production of cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed