Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50026494
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251762BDBM50251762(6-(3-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251821BDBM50251821(3-ethyl-6-(phenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251729BDBM50251729(6-(2-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataKi:  14nMAssay Description:Inhibition of 5HT2CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251692BDBM50251692(6-(4-chlorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251729BDBM50251729(6-(2-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251690BDBM50251690(6-(2-chlorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251763BDBM50251763(6-(3-methoxyphenylsulfonyl)-3-methyl-1,2,3,4,5,6-h...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251689BDBM50251689(6-(4-fluorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251728BDBM50251728(6-(5-chloronaphthalen-2-ylsulfonyl)-1,2,3,4,5,6-he...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251694BDBM50251694(6-tosyl-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole ...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251730BDBM50251730(6-(4-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251654BDBM50251654(6-(3-fluorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251691BDBM50251691(6-(3-chlorophenylsulfonyl)-1,2,3,4,5,6-hexahydroaz...)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251727BDBM50251727(6-(4-(trifluoromethyl)phenylsulfonyl)-1,2,3,4,5,6-...)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251764BDBM50251764(3-ethyl-6-(3-methoxyphenylsulfonyl)-1,2,3,4,5,6-he...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251693BDBM50251693(6-(m-tolylsulfonyl)-1,2,3,4,5,6-hexahydroazepino[4...)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251766BDBM50251766(3-isopropyl-6-(3-methoxyphenylsulfonyl)-1,2,3,4,5,...)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251726BDBM50251726(6-(3-(trifluoromethyl)phenylsulfonyl)-1,2,3,4,5,6-...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251765BDBM50251765(6-(3-methoxyphenylsulfonyl)-3-propyl-1,2,3,4,5,6-h...)
Affinity DataKi:  124nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251790BDBM50251790(3-benzyl-6-(3-methoxyphenylsulfonyl)-1,2,3,4,5,6-h...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251729BDBM50251729(6-(2-methoxyphenylsulfonyl)-1,2,3,4,5,6-hexahydroa...)
Affinity DataIC50: 162nMAssay Description:Antagonist activity at cloned human 5HT6 receptor expressed in HeLa cells assessed as production of cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251653BDBM50251653(6-(phenylsulfonyl)-1,2,3,4,5,6-hexahydroazepino[4,...)
Affinity DataKi:  193nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251793BDBM50251793(3-cyclohexyl-6-(3-methoxyphenylsulfonyl)-1,2,3,4,5...)
Affinity DataKi:  253nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251792BDBM50251792(3-cyclopentyl-6-(3-methoxyphenylsulfonyl)-1,2,3,4,...)
Affinity DataKi:  324nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50251791BDBM50251791(6-(3-methoxyphenylsulfonyl)-3-phenethyl-1,2,3,4,5,...)
Affinity DataKi:  504nMAssay Description:Displacement of [3H]-LSD from cloned human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed