Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50026634
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261879(2-Methyl-c-5-{4-[2-(5-methyl-2-(5-methylthiophen-2...)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50256109((2s,5s)-2-methyl-5-(4-((5-methyl-2-p-tolyloxazol-4...)
Affinity DataEC50:  0.0720nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261703(2-Methyl-c-5-{4-[2-(5-methyl-2-(4-methylphenyl)oxa...)
Affinity DataEC50:  0.0890nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261702(2-Methyl-c-5-[4-{2-(5-methyl-2-phenyloxazol-4-yl)e...)
Affinity DataEC50:  0.272nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261878(2-Methyl-c-5-{4-[5-methyl-2-(5-methylthiophen-2-yl...)
Affinity DataEC50:  0.600nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261701(2-Methyl-c-5-[4-(5-methyl-2-phenyloxazol-4-ylmetho...)
Affinity DataEC50:  1.09nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261880(c-5-[4-{2-(2-tert-Butyl-5-methyloxazol-4-yl)ethoxy...)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50256109((2s,5s)-2-methyl-5-(4-((5-methyl-2-p-tolyloxazol-4...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261878(2-Methyl-c-5-{4-[5-methyl-2-(5-methylthiophen-2-yl...)
Affinity DataEC50:  19.8nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM28681(cid_5281055 | [3H]rosiglitazone | CHEMBL121 | ROSI...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261701(2-Methyl-c-5-[4-(5-methyl-2-phenyloxazol-4-ylmetho...)
Affinity DataEC50:  96nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261879(2-Methyl-c-5-{4-[2-(5-methyl-2-(5-methylthiophen-2...)
Affinity DataEC50:  239nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261703(2-Methyl-c-5-{4-[2-(5-methyl-2-(4-methylphenyl)oxa...)
Affinity DataEC50:  1.39E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261702(2-Methyl-c-5-[4-{2-(5-methyl-2-phenyloxazol-4-yl)e...)
Affinity DataEC50:  4.10E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM24566(JMC515449 Compound 1 | Wyeth 14,643 | 2-({4-chloro...)
Affinity DataEC50:  4.80E+3nMAssay Description:Agonist activity at PPARalpha expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50261880(c-5-[4-{2-(2-tert-Butyl-5-methyloxazol-4-yl)ethoxy...)
Affinity DataEC50:  5.01E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HepG2 cells assessed as induction of receptor transactivation by reporter gene assay relative to con...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed