Compile Data Set for Download or QSAR
maximum 50k data
Found 24 Enz. Inhib. hit(s) with all data for entry = 2795
TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24722(7,7,16-trimethyl-5,11,14,15-tetraazapentacyclo[10....)
Affinity DataIC50: <2nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24722(7,7,16-trimethyl-5,11,14,15-tetraazapentacyclo[10....)
Affinity DataIC50:  2nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24721(5-ethyl-7,7,16-trimethyl-5,11,14,15-tetraazapentac...)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24721(5-ethyl-7,7,16-trimethyl-5,11,14,15-tetraazapentac...)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50:  6nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24720(5-methyl-3,4,17-triazatetracyclo[8.7.0.0^{2,6}.0^{...)
Affinity DataIC50:  22nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM13534(CHEMBL572878 | N-[4-({4-[(3-methyl-1H-pyrazol-5-yl...)
Affinity DataIC50:  30nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24720(5-methyl-3,4,17-triazatetracyclo[8.7.0.0^{2,6}.0^{...)
Affinity DataIC50:  42nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24714(5-methyl-3,4,16-triazatetracyclo[7.7.0.0^{2,6}.0^{...)
Affinity DataIC50:  51nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24712(5-ethyl-7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-...)
Affinity DataIC50:  69nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24723(5,5,16-trimethyl-7,11,14,15-tetraazapentacyclo[10....)
Affinity DataIC50:  72nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24723(5,5,16-trimethyl-7,11,14,15-tetraazapentacyclo[10....)
Affinity DataIC50:  86nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24715(5-cyclopropyl-3,4,16-triazatetracyclo[7.7.0.0^{2,6...)
Affinity DataIC50:  110nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24712(5-ethyl-7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-...)
Affinity DataIC50:  130nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24711(7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-1H,5H,6H...)
Affinity DataIC50:  150nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24711(7,7-dimethyl-2-(5-methyl-1H-pyrazol-3-yl)-1H,5H,6H...)
Affinity DataIC50:  180nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24714(5-methyl-3,4,16-triazatetracyclo[7.7.0.0^{2,6}.0^{...)
Affinity DataIC50:  220nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24713(1,2,4,5-tetrahydropyrazolo[3,4-a]carbazole | 3,4,1...)
Affinity DataIC50:  300nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24717(3,4,16-triazatetracyclo[7.7.0.0^{2,6}.0^{10,15}]he...)
Affinity DataIC50:  340nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24718(2-(5-Methyl-1H-pyrazol-3-yl)-1H-indole | pyrazole-...)
Affinity DataIC50:  510nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24719(13-methyl-8,11,12-triazatetracyclo[7.6.0.0^{2,7}.0...)
Affinity DataIC50:  870nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Genentech

LigandPNGBDBM24719(13-methyl-8,11,12-triazatetracyclo[7.6.0.0^{2,7}.0...)
Affinity DataIC50:  880nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24718(2-(5-Methyl-1H-pyrazol-3-yl)-1H-indole | pyrazole-...)
Affinity DataIC50:  1.10E+3nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Genentech

LigandPNGBDBM24716(Tetrahydropyrazolo[3,4-a]carbazole, 25 | ethyl 3,4...)
Affinity DataIC50:  5.70E+3nMpH: 7.5 T: 2°CAssay Description:Aurora kinase was assayed in ELISA format using a GST fusion of the N-terminus of Histone H3 as substrate. Plates were coated with substrate, and the...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed