Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50038648
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272893(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272853(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272855(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272817(1-(2-chlorophenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272892(1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(3-(1-eth...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272854(1-(3-chlorophenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3...)
Affinity DataIC50: 10.5nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272783(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50: 17.4nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272852(1-(2,6-difluorophenyl)-3-(3-(1-ethyl-4-(1H-pyrrolo...)
Affinity DataIC50: 25.7nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50377952(CHEMBL1964273)
Affinity DataIC50: 33.9nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272814(1-cyclohexyl-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyr...)
Affinity DataIC50: 41.7nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50377951(CHEMBL1964274)
Affinity DataIC50: 45.7nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272853(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50: 63nMAssay Description:Inhibition of B-Raf-mediated phosphorylation of MEK1 in mouse 3T3 cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272894(1-(3-(4-(3-bromo-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-...)
Affinity DataIC50: 79.4nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272816(1-(4-(benzyloxy)phenyl)-3-(3-(1-ethyl-4-(1H-pyrrol...)
Affinity DataIC50: 110nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272815(1-benzyl-3-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin...)
Affinity DataIC50: 170nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272893(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50: 200nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272893(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50: 316nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272782(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50: 331nMAssay Description:Inhibition of B-Raf by fluorescence anisotropy binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272853(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50272853(1-(3-(1-ethyl-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1H...)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed