Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50026758
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273030BDBM50273030((E)-2-(5-Fluoro-1-(naphthalen-1-ylmethylene)-1H-in...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273067BDBM50273067((E)-2-(1-((2,4-Difluorobiphenyl-4-yl)methylene)-5-...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273065BDBM50273065((E)-2-(1-(Biphenyl-4-ylmethylene)-5-fluoro-1H-inde...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273031BDBM50273031((E)-2-(5-Fluoro-1-((4-fluoronaphthalen-1-yl)methyl...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273027BDBM50273027((E)-2-(5-Fluoro-1-(4-(trifluoromethylthio)benzylid...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272862BDBM50272862((E)-2'-des-methyl sulindac sulfide | 2-desmethylsu...)
Affinity DataEC50:  700nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50110164BDBM50110164({6-Fluoro-2-methyl-3-[1-(4-methylsulfanyl-phenyl)-...)
Affinity DataEC50:  800nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272986BDBM50272986((E)-2-(1-(4-(Azidomethyl)benzylidene)-5-fluoro-1H-...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272985BDBM50272985((E)-2-(1-(4-Ethynylbenzylidene)-5-fluoro-1H-inden-...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272903BDBM50272903((E)-2-(1-(4-Bromobenzylidene)-5-fluoro-1H-inden-3-...)
Affinity DataEC50:  1.10E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273028BDBM50273028((E)-2-(5-Fluoro-1-(naphthalen-2-ylmethylene)-1H-in...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272987BDBM50272987((E)-2-(5-Fluoro-1-(4-methoxybenzylidene)-1H-inden-...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273066BDBM50273066((E)-2-(5-Fluoro-1-((4-(methylthio)biphenyl-4-yl)me...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273064BDBM50273064((E)-2-(5-Fluoro-1-(quinolin-8-ylmethylene)-1H-inde...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272905BDBM50272905((E)-2-(1-Benzylidene-5-fluoro-1H-inden-3-yl)ethano...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272988BDBM50272988((E)-2-(1-(4-tert-Butoxybenzylidene)-5-fluoro-1H-in...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272906BDBM50272906((E)-2-(5-Fluoro-1-(4-methylbenzylidene)-1H-inden-3...)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272984BDBM50272984((E)-2-(5-Fluoro-1-(4-(trifluoromethyl)benzylidene)...)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50273029BDBM50273029((E)-2-(5-Fluoro-1-(quinoxalin-6-ylmethylene)-1H-in...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272904BDBM50272904(2-(5-Fluoro-1H-inden-3-yl)ethanoic acid | CHEMBL50...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272902BDBM50272902((E)-4-((3-(Carboxymethyl)-5-fluoro-1H-inden-1-ylid...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272861BDBM50272861((E)-2-(5-Fluoro-1-(4-(methylsulfinyl)benzylidene)-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Vanderbilt University Center For Structural Biology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272901BDBM50272901((E)-2-(5-Fluoro-1-(4-(methylsulfonyl)benzylidene)-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at PPARgamma expressed in human HCA7 cells assessed as induction of peroxisome proliferator response element after 12 hrs by lucifer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed