Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50026797
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272197BDBM50272197(2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-phenyl-...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272372BDBM50272372(2-(naphthalen-1-yl)-1-(4-phenyl-2-(pyrrolidin-1-yl...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272373BDBM50272373(2-(5-chlorobenzo[b]thiophen-3-yl)-1-(4-phenyl-2-(p...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272371BDBM50272371(2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-(methyl...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50241425BDBM50241425(2-((3,4-dichlorophenyl)(methyl)amino)-1-(2-(pyrrol...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272196BDBM50272196(2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-(3-meth...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272374BDBM50272374(1-(4-phenyl-2-(pyrrolidin-1-ylmethyl)piperazin-1-y...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272252BDBM50272252(1-(4-(3-chlorophenyl)-2-(pyrrolidin-1-ylmethyl)pip...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272198BDBM50272198(2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-(3,4-di...)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272326BDBM50272326(2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-(3-meth...)
Affinity DataEC50:  79nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272324BDBM50272324(TCMDC-136893 | 1-(4-(3-chlorophenylsulfonyl)-2-(py...)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272295BDBM50272295(2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-(phenyl...)
Affinity DataEC50:  250nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272476BDBM50272476(5-chloro-3-(2-(4-(3,4-dimethoxyphenylsulfonyl)-2-(...)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272474BDBM50272474(5-chloro-3-(2-(4-(3-methoxyphenylsulfonyl)-2-(pyrr...)
Affinity DataEC50:  320nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272327BDBM50272327(2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-(3,4-di...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272411BDBM50272411(3-(2-oxo-2-(4-phenyl-2-(pyrrolidin-1-ylmethyl)pipe...)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272293BDBM50272293(2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-isonico...)
Affinity DataEC50:  630nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272414BDBM50272414(3-(4-(2-(5-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)ace...)
Affinity DataEC50:  630nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272498BDBM50272498(3-(2-(4-(5-bromo-2-methoxyphenylsulfonyl)-2-(pyrro...)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272325BDBM50272325(1-(4-(4-chlorophenylsulfonyl)-2-(pyrrolidin-1-ylme...)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272413BDBM50272413(5-chloro-3-(2-oxo-2-(4-(phenylsulfonyl)-2-(pyrroli...)
Affinity DataEC50:  790nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272446BDBM50272446(5-chloro-3-(2-(4-(2-chloro-5-(trifluoromethyl)phen...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272412BDBM50272412(3-(2-oxo-2-(4-(phenylsulfonyl)-2-(pyrrolidin-1-ylm...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272499BDBM50272499(N-(4-(4-(2-(5-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272497BDBM50272497(3-(2-(4-(2-bromo-3,4-dimethoxyphenylsulfonyl)-2-(p...)
Affinity DataEC50:  1.30E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272475BDBM50272475(5-chloro-3-(2-(4-(4-methoxyphenylsulfonyl)-2-(pyrr...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272445BDBM50272445(3-(2-(4-(2-bromophenylsulfonyl)-2-(pyrrolidin-1-yl...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272444BDBM50272444(5-chloro-3-(2-oxo-2-(2-(pyrrolidin-1-ylmethyl)-4-(...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272531BDBM50272531(4-(4-(2-(5-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)ace...)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272292BDBM50272292(4-(1-(2-((3,4-dichlorophenyl)(methyl)amino)acetyl)...)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272253BDBM50272253(4-(2-((3,4-dichlorophenyl)(methyl)amino)acetyl)-N-...)
Affinity DataEC50:  4.00E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272254BDBM50272254(1-(4-benzoyl-2-(pyrrolidin-1-ylmethyl)piperazin-1-...)
Affinity DataEC50:  7.90E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272532BDBM50272532(4-(4-(2-(5-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)ace...)
Affinity DataEC50:  7.90E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272294BDBM50272294(1-(4-(3-chlorobenzoyl)-2-(pyrrolidin-1-ylmethyl)pi...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50272255BDBM50272255(2-((3,4-dichlorophenyl)(methyl)amino)-1-(4-(3,4-di...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO-K1 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed