Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50026801
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50156455((R)-N-(4-(4,5-dihydro-1H-imidazol-2-yl)phenethyl)-...)
Affinity DataKi:  0.0340nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272453(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272455(2-((R)-3-oxo-1-(phenylsulfonyl)-1,2,3,4-tetrahydro...)
Affinity DataIC50: 0.120nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272456(2-((R)-3-oxo-1-tosyl-1,2,3,4-tetrahydroquinoxalin-...)
Affinity DataIC50: 0.140nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272452(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataKi:  0.150nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50156455((R)-N-(4-(4,5-dihydro-1H-imidazol-2-yl)phenethyl)-...)
Affinity DataIC50: 0.180nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272455(2-((R)-3-oxo-1-(phenylsulfonyl)-1,2,3,4-tetrahydro...)
Affinity DataKi:  0.190nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272456(2-((R)-3-oxo-1-tosyl-1,2,3,4-tetrahydroquinoxalin-...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272454(N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-2-...)
Affinity DataIC50: 0.370nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272450(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272452(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataIC50: 0.480nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272453(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataIC50: 0.550nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272449(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272447(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272449(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataIC50: 0.860nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272448(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272451(N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-2-...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272416(N-((R)-7-(aminomethyl)chroman-4-yl)-2-((R)-1-(3,4-...)
Affinity DataIC50: 1.20nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272447(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272450(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataIC50: 1.40nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272448(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataKi:  1.70nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272451(N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-2-...)
Affinity DataIC50: 1.70nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272454(N-((R)-7-((tert-butylamino)methyl)chroman-4-yl)-2-...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272416(N-((R)-7-(aminomethyl)chroman-4-yl)-2-((R)-1-(3,4-...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50182221(N-((R)-6-((tert-butylamino)methyl)-1,2,3,4-tetrahy...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50182221(N-((R)-6-((tert-butylamino)methyl)-1,2,3,4-tetrahy...)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272478(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272478(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataKi:  57nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272477(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataIC50: 62nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272477(2-((R)-1-(3,4-dichlorophenylsulfonyl)-3-oxo-1,2,3,...)
Affinity DataKi:  86nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272415(2-(1-(mesitylsulfonyl)-3-oxo-1,2,3,4-tetrahydronox...)
Affinity DataKi:  500nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHO-D-/aequorin cells by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetB1 bradykinin receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50272415(2-(1-(mesitylsulfonyl)-3-oxo-1,2,3,4-tetrahydronox...)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed