Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50038680
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50331515(PAROXETINE | Paxil | CHEMBL1708 | Paxil cr | Parox...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM21393(cid_1220 | CHEMBL56 | 7-(dipropylamino)-5,6,7,8-te...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263946(6-(1H-imidazol-1-yl)-2-(4-(4-(2-isopropoxyphenyl)p...)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263947(6-(1H-imidazol-1-yl)-2-(4-(4-(3-(trifluoromethyl)p...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263945(2-(4-(4-(2-ethoxyphenyl)piperazin-1-yl)butyl)-6-(1...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264009(6-(1H-indol-1-yl)-2-(4-(4-(2-isopropoxyphenyl)pipe...)
Affinity DataKi:  22.8nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264008(2-(4-(4-(2-ethoxyphenyl)piperazin-1-yl)butyl)-6-(1...)
Affinity DataKi:  27.7nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264010(6-(1H-indol-1-yl)-2-(4-(4-(3-(trifluoromethyl)phen...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264010(6-(1H-indol-1-yl)-2-(4-(4-(3-(trifluoromethyl)phen...)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]ketanserine from 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264010(6-(1H-indol-1-yl)-2-(4-(4-(3-(trifluoromethyl)phen...)
Affinity DataKi:  109nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263947(6-(1H-imidazol-1-yl)-2-(4-(4-(3-(trifluoromethyl)p...)
Affinity DataKi:  166nMAssay Description:Displacement of [3H]ketanserine from 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264060(2-(4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)piper...)
Affinity DataKi:  177nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264058(6-(1H-indol-1-yl)-2-(4-(4-(pyrimidin-2-yl)piperazi...)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263947(6-(1H-imidazol-1-yl)-2-(4-(4-(3-(trifluoromethyl)p...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50117128(6-Indol-1-yl-2-{4-[4-(2-methoxy-phenyl)-piperazin-...)
Affinity DataKi:  253nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264061(6-(1H-imidazol-1-yl)-2-(4-(4-(2-methoxyphenyl)pipe...)
Affinity DataKi:  318nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264060(2-(4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)piper...)
Affinity DataKi:  627nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264008(2-(4-(4-(2-ethoxyphenyl)piperazin-1-yl)butyl)-6-(1...)
Affinity DataKi:  639nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264011(6-(1H-imidazol-1-yl)-2-(4-(4-(pyrimidin-2-yl)piper...)
Affinity DataKi:  890nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264059(2-(4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)piper...)
Affinity DataKi:  937nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264061(6-(1H-imidazol-1-yl)-2-(4-(4-(2-methoxyphenyl)pipe...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263312(2-(4-(4-(2-ethoxyphenyl)piperazin-1-yl)-4-oxobutyl...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263313(6-(1H-imidazol-1-yl)-2-(4-(4-(2-isopropoxyphenyl)p...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263352(2-(3-(1H-imidazol-1-yl)-6-oxopyridazin-1(6H)-yl)-N...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264009(6-(1H-indol-1-yl)-2-(4-(4-(2-isopropoxyphenyl)pipe...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263315(2-(3-(1H-imidazol-1-yl)-6-oxopyridazin-1(6H)-yl)-N...)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263313(6-(1H-imidazol-1-yl)-2-(4-(4-(2-isopropoxyphenyl)p...)
Affinity DataKi:  1.56E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263352(2-(3-(1H-imidazol-1-yl)-6-oxopyridazin-1(6H)-yl)-N...)
Affinity DataKi:  1.91E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263314(2-(3-(1H-imidazol-1-yl)-6-oxopyridazin-1(6H)-yl)-N...)
Affinity DataKi:  2.07E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263312(2-(4-(4-(2-ethoxyphenyl)piperazin-1-yl)-4-oxobutyl...)
Affinity DataKi:  2.25E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in rat cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263314(2-(3-(1H-imidazol-1-yl)-6-oxopyridazin-1(6H)-yl)-N...)
Affinity DataKi:  3.46E+3nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263315(2-(3-(1H-imidazol-1-yl)-6-oxopyridazin-1(6H)-yl)-N...)
Affinity DataKi:  5.98E+3nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264058(6-(1H-indol-1-yl)-2-(4-(4-(pyrimidin-2-yl)piperazi...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264059(2-(4-(4-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)piper...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263945(2-(4-(4-(2-ethoxyphenyl)piperazin-1-yl)butyl)-6-(1...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50263946(6-(1H-imidazol-1-yl)-2-(4-(4-(2-isopropoxyphenyl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50264011(6-(1H-imidazol-1-yl)-2-(4-(4-(pyrimidin-2-yl)piper...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]paroxetine from SERT in human platelet membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMed