Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50004140
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479316BDBM50479316(CHEMBL515000)
Affinity DataIC50: 550nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15408BDBM15408(2,5-dichloro-N-[4-hydroxy-3-(2-hydroxynaphthalen-1...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479314BDBM50479314(CHEMBL478665)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479310BDBM50479310(CHEMBL476157)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479313BDBM50479313(CHEMBL478879)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479318BDBM50479318(CHEMBL478664)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479315BDBM50479315(CHEMBL476359)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15402BDBM15402(N-[4-hydroxy-3-(2-hydroxynaphthalen-1-yl)phenyl]be...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479312BDBM50479312(CHEMBL477824)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479317BDBM50479317(CHEMBL477825)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479309BDBM50479309(CHEMBL476368)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32168BDBM32168(TG2-90-1 | cid_16072262 | 2,5-bis(chloranyl)-N-[3-...)
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479308BDBM50479308(CHEMBL478890)
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 15408BDBM15408(2,5-dichloro-N-[4-hydroxy-3-(2-hydroxynaphthalen-1...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as Her2 degradation after 24 hrs by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479316BDBM50479316(CHEMBL515000)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as Her2 degradation after 24 hrs by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479311BDBM50479311(CHEMBL514704)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32195BDBM32195(cid_16072279 | 4-chloranyl-N-[4-fluoranyl-3-(5-oxi...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32194BDBM32194(TG1-268-1 | 3-cyano-4-fluoranyl-N-[4-fluoranyl-3-(...)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 32151BDBM32151(N-[4-fluoro-3-(5-hydroxy-1,3-benzodioxol-4-yl)phen...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Emory University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50479319BDBM50479319(CHEMBL476369)
Affinity DataIC50: 3.13E+4nMAssay Description:Inhibition of Hsp90 in human SKBR3 cells assessed as interaction with Cy3b-conjugated geldanamycin by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed