Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 2809
TargetSerine/threonine-protein kinase PLK2(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24933(3-(2H-1,3-benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]...)
Affinity DataIC50: 4nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24933(3-(2H-1,3-benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]...)
Affinity DataIC50: 24nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24935(3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}pyrido...)
Affinity DataIC50: 51nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24934(3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}pyrido...)
Affinity DataIC50: 99nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24926(1-(3-chlorophenyl)-3-methyl-N-[(1S)-1-phenylethyl]...)
Affinity DataIC50: 121nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24935(3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}pyrido...)
Affinity DataIC50: 172nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24933(3-(2H-1,3-benzodioxol-5-yl)-N-[(1S)-1-phenylethyl]...)
Affinity DataIC50: 214nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24930(3-(3,5-dimethylphenyl)-N-[(1S)-1-phenylethyl]pyrid...)
Affinity DataIC50: 330nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24928(3-(3-methylphenyl)-N-[(1S)-1-phenylethyl]pyrido[4,...)
Affinity DataIC50: 549nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24931(3-(3-chlorophenyl)-N-[(1S)-1-phenylethyl]pyrido[4,...)
Affinity DataIC50: 625nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24938(3-(4-methylthiophen-3-yl)-N-[(1S)-1-phenylethyl]py...)
Affinity DataIC50: 779nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24929(3-(4-methylphenyl)-N-[(1S)-1-phenylethyl]pyrido[4,...)
Affinity DataIC50: 1.17E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24925(BMCL185648 Compound 1 | 3-methyl-1-phenyl-N-[(1S)-...)
Affinity DataIC50: 1.30E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24935(3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}pyrido...)
Affinity DataIC50: 1.38E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24928(3-(3-methylphenyl)-N-[(1S)-1-phenylethyl]pyrido[4,...)
Affinity DataIC50: 1.45E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24927(3-phenyl-N-[(1S)-1-phenylethyl]pyrido[4,3-d][1,2]o...)
Affinity DataIC50: 1.62E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24937(N-[(1S)-1-phenylethyl]-3-(thiophen-2-yl)pyrido[4,3...)
Affinity DataIC50: 3.01E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24932(3-(3,4-dimethoxyphenyl)-N-[(1S)-1-phenylethyl]pyri...)
Affinity DataIC50: 4.93E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24939(3-(2-methylcyclohexyl)-N-[(1S)-1-phenylethyl]pyrid...)
Affinity DataIC50: 5.69E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24940(3-[3-(5-{[(1S)-1-phenylethyl]amino}pyrido[4,3-d][1...)
Affinity DataIC50: 7.48E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24928(3-(3-methylphenyl)-N-[(1S)-1-phenylethyl]pyrido[4,...)
Affinity DataIC50: 1.00E+4nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24936(3-benzyl-N-[(1S)-1-phenylethyl]pyrido[4,3-d][1,2]o...)
Affinity DataIC50: 2.00E+4nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed