Compile Data Set for Download or QSAR
maximum 50k data
Found 15 Enz. Inhib. hit(s) with all data for entry = 50041681
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413094(CHEMBL486116)
Affinity DataIC50:  18.6nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413093(CHEMBL528990)
Affinity DataIC50:  19.5nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413092(CHEMBL519258)
Affinity DataIC50:  25.1nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413100(CHEMBL485915)
Affinity DataIC50:  51.3nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413098(CHEMBL485716)
Affinity DataIC50:  81.3nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413102(CHEMBL486542)
Affinity DataIC50:  107nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413095(CHEMBL486117)
Affinity DataIC50:  110nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413101(CHEMBL486747)
Affinity DataIC50:  132nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413097(CHEMBL521024)
Affinity DataIC50:  138nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413096(CHEMBL486323)
Affinity DataIC50:  151nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413099(CHEMBL485717)
Affinity DataIC50:  195nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413090(CHEMBL487979)
Affinity DataIC50:  229nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413088(CHEMBL487576)
Affinity DataIC50:  302nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413091(CHEMBL487980)
Affinity DataIC50:  324nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50413089(CHEMBL487782)
Affinity DataIC50:  562nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed