Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50041681
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413094BDBM50413094(CHEMBL486116)
Affinity DataIC50: 18.6nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413093BDBM50413093(CHEMBL528990)
Affinity DataIC50: 19.5nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413092BDBM50413092(CHEMBL519258)
Affinity DataIC50: 25.1nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413100BDBM50413100(CHEMBL485915)
Affinity DataIC50: 51.3nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413098BDBM50413098(CHEMBL485716)
Affinity DataIC50: 81.3nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413102BDBM50413102(CHEMBL486542)
Affinity DataIC50: 107nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413095BDBM50413095(CHEMBL486117)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413101BDBM50413101(CHEMBL486747)
Affinity DataIC50: 132nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413097BDBM50413097(CHEMBL521024)
Affinity DataIC50: 138nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413096BDBM50413096(CHEMBL486323)
Affinity DataIC50: 151nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413099BDBM50413099(CHEMBL485717)
Affinity DataIC50: 195nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413090BDBM50413090(CHEMBL487979)
Affinity DataIC50: 229nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413088BDBM50413088(CHEMBL487576)
Affinity DataIC50: 302nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413091BDBM50413091(CHEMBL487980)
Affinity DataIC50: 324nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Pharmacopeia

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50413089BDBM50413089(CHEMBL487782)
Affinity DataIC50: 562nMAssay Description:Antagonist activity at human OX2 receptor expressed in HEK293 cells assessed as inhibition of human orexin-A-stimulated calcium release by FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed