Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 2865
LigandChemical structure of BindingDB Monomer ID 25494BDBM25494(4-(4-chloro-2-fluorophenyl)-N-(1H-indazol-5-yl)-2-...)
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25495BDBM25495(4-(4-chloro-2-fluorophenyl)-N-(1H-indazol-5-yl)-2-...)
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25493BDBM25493(4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-y...)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25492BDBM25492(4-(4-chloro-2-fluorophenyl)-N-(1H-indazol-5-yl)-2-...)
Affinity DataIC50: 5nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25496BDBM25496(4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-y...)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25498BDBM25498(4-(4-chloro-2-fluorophenyl)-N-(6-fluoro-1H-indazol...)
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25483BDBM25483(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25500BDBM25500(4-(4-chloro-2-fluorophenyl)-N-(6-fluoro-1H-indazol...)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25499BDBM25499(4-(4-chloro-2-fluorophenyl)-2-(2-ethoxypyridin-4-y...)
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 14048BDBM14048(JMC516631 Compound 1 | 4-(4-fluorophenyl)-N-(1H-in...)
Affinity DataIC50: 14nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25497BDBM25497(4-(4-chloro-2-fluorophenyl)-2-(2-chloropyridin-4-y...)
Affinity DataIC50: 15nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25491BDBM25491(4-[2-fluoro-4-(trifluoromethyl)phenyl]-N-(1H-indaz...)
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25478BDBM25478(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-2-(4-methox...)
Affinity DataIC50: 46nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25490BDBM25490(N-(1H-indazol-5-yl)-2-(4-methoxyphenyl)-6-methyl-4...)
Affinity DataIC50: 68nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25487BDBM25487(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50: 75nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25479BDBM25479(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50: 101nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25480BDBM25480(2-(3-fluoro-4-methylphenyl)-4-(4-fluorophenyl)-N-(...)
Affinity DataIC50: 104nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25477BDBM25477(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50: 105nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25484BDBM25484(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50: 105nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25481BDBM25481(2-(4-chlorophenyl)-4-(4-fluorophenyl)-N-(1H-indazo...)
Affinity DataIC50: 129nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25482BDBM25482(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50: 129nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25488BDBM25488(N-(1H-indazol-5-yl)-4-(4-methanesulfonylphenyl)-2-...)
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25486BDBM25486(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50: 180nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25485BDBM25485(4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-2-...)
Affinity DataIC50: 288nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 25489BDBM25489(N-(1H-indazol-5-yl)-2-(4-methoxyphenyl)-4,6-dimeth...)
Affinity DataIC50: 863nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed