Compile Data Set for Download or QSAR
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Found 44 Enz. Inhib. hit(s) with all data for entry = 50027393
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274090(4-({(S)-2-[(3S,4S)-4-[(S)-2-((S)-2-tert-Butoxycarb...)
Affinity DataKi:  15nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274091(4-({(S)-2-[(3S,4S)-4-[(S)-2-((S)-2-tert-Butoxycarb...)
Affinity DataKi:  24nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274096(4-[((S)-2-{(3S,4S)-5-Benzyloxy-3-hydroxy-4-[3-(met...)
Affinity DataKi:  180nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274103(5-{(S)-2-[(3S,4S)-5-Benzyloxy-4-(3-dipropylcarbamo...)
Affinity DataKi:  350nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274094(4-[((S)-2-{(3S,4S)-3-Hydroxy-4-[3-(methanesulfonyl...)
Affinity DataKi:  360nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274095(4-[((S)-2-{(3S,4S)-5-(3,5-Difluoro-benzyloxy)-3-hy...)
Affinity DataKi:  430nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274100(5-((S)-2-{(3S,4S)-5-(3,5-Difluoro-benzyloxy)-3-hyd...)
Affinity DataKi:  440nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274093(4-[((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydr...)
Affinity DataKi:  510nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274108(CHEMBL445085 | N-[(1S,2S)-3-((S)-1-Benzylcarbamoyl...)
Affinity DataKi:  570nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274101(5-((S)-2-{(3S,4S)-5-Benzyloxy-3-hydroxy-4-[3-(meth...)
Affinity DataKi:  630nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274092(4-[((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydr...)
Affinity DataKi:  730nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274099(5-((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydro...)
Affinity DataKi:  780nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274102(5-{(S)-2-[(3S,4S)-5-(3,5-Difluoro-benzyloxy)-4-(3-...)
Affinity DataKi:  930nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274109(4-((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydro...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274098(5-((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydro...)
Affinity DataKi:  1.95E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274111(4-[((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydr...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274110(4-[((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydr...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274107(4-[(2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydroxy-...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274106(4-({(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydroxy-4-[...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274105(CHEMBL455292 | N-[(1S,2S)-3-Cyclopropylcarbamoyl-1...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274104(5-((S)-2-{(3S,4S)-5-(3,5-Difluoro-benzyloxy)-3-hyd...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274097(4-[((S)-2-{(3R,4S)-5-Benzyloxy-3-hydroxy-4-[3-(met...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274101(5-((S)-2-{(3S,4S)-5-Benzyloxy-3-hydroxy-4-[3-(meth...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274093(4-[((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydr...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274094(4-[((S)-2-{(3S,4S)-3-Hydroxy-4-[3-(methanesulfonyl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274096(4-[((S)-2-{(3S,4S)-5-Benzyloxy-3-hydroxy-4-[3-(met...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274099(5-((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydro...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274100(5-((S)-2-{(3S,4S)-5-(3,5-Difluoro-benzyloxy)-3-hyd...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274095(4-[((S)-2-{(3S,4S)-5-(3,5-Difluoro-benzyloxy)-3-hy...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274092(4-[((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydr...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274108(CHEMBL445085 | N-[(1S,2S)-3-((S)-1-Benzylcarbamoyl...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274098(5-((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydro...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274109(4-((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydro...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274097(4-[((S)-2-{(3R,4S)-5-Benzyloxy-3-hydroxy-4-[3-(met...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274104(5-((S)-2-{(3S,4S)-5-(3,5-Difluoro-benzyloxy)-3-hyd...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274103(5-{(S)-2-[(3S,4S)-5-Benzyloxy-4-(3-dipropylcarbamo...)
Affinity DataIC50:  1.89E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274102(5-{(S)-2-[(3S,4S)-5-(3,5-Difluoro-benzyloxy)-4-(3-...)
Affinity DataIC50:  2.23E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274107(4-[(2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydroxy-...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274106(4-({(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydroxy-4-[...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274090(4-({(S)-2-[(3S,4S)-4-[(S)-2-((S)-2-tert-Butoxycarb...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274091(4-({(S)-2-[(3S,4S)-4-[(S)-2-((S)-2-tert-Butoxycarb...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274111(4-[((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274105(CHEMBL455292 | N-[(1S,2S)-3-Cyclopropylcarbamoyl-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
LinköPing University

Curated by ChEMBL
LigandPNGBDBM50274110(4-[((S)-2-{(3S,4S)-5-(3,5-Difluoro-phenoxy)-3-hydr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) by resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed