Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50027415
TargetSerine/threonine-protein kinase PLK3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275752BDBM50275752(5-methyl-7-(3-(trifluoromethyl)phenyl)-N-(3,4,5-tr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PLK3 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275752BDBM50275752(5-methyl-7-(3-(trifluoromethyl)phenyl)-N-(3,4,5-tr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275665BDBM50275665(5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidaz...)
Affinity DataIC50: 40nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275702BDBM50275702(7-(3-bromophenyl)-5-methyl-N-(3,4,5-trimethoxyphen...)
Affinity DataIC50: 70nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275806BDBM50275806(7-(4-fluorophenyl)-5-methyl-N-(3,4,5-trimethoxyphe...)
Affinity DataIC50: 80nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275664BDBM50275664(N-(3,4-dimethoxyphenyl)-5-methyl-7-phenylimidazo[1...)
Affinity DataIC50: 90nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275665BDBM50275665(5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidaz...)
Affinity DataIC50: 90nMAssay Description:Inhibition of PLK3 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275665BDBM50275665(5-methyl-7-phenyl-N-(3,4,5-trimethoxyphenyl)imidaz...)
Affinity DataIC50: 230nMAssay Description:Inhibition of CDK2/cyclin AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275626BDBM50275626(N-(3-methoxyphenyl)-5-methyl-7-phenylimidazo[1,5-f...)
Affinity DataIC50: 300nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275628BDBM50275628(N-(4-(2-(dimethylamino)ethoxy)phenyl)-5-methyl-7-p...)
Affinity DataIC50: 380nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275754BDBM50275754((3-(5-methyl-2-(3,4,5-trimethoxyphenylamino)imidaz...)
Affinity DataIC50: 410nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275755BDBM50275755(5-methyl-7-(3-phenoxyphenyl)-N-(3,4,5-trimethoxyph...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275627BDBM50275627(N-(4-methoxyphenyl)-5-methyl-7-phenylimidazo[1,5-f...)
Affinity DataIC50: 680nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275753BDBM50275753(5-methyl-7-(4-(trifluoromethyl)phenyl)-N-(3,4,5-tr...)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275625BDBM50275625(5-methyl-N,7-diphenylimidazo[1,5-f][1,2,4]triazin-...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275589BDBM50275589(N-benzyl-5-methyl-7-phenylimidazo[1,5-f][1,2,4]tri...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275700BDBM50275700(5-methyl-7-(2-nitrophenyl)-N-(3,4,5-trimethoxyphen...)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275701BDBM50275701(7-(2-bromophenyl)-5-methyl-N-(3,4,5-trimethoxyphen...)
Affinity DataIC50: 2.67E+3nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275663BDBM50275663(4-(5-methyl-7-phenylimidazo[1,5-f][1,2,4]triazin-2...)
Affinity DataIC50: 2.74E+3nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275662BDBM50275662(5-methyl-N-(4-nitrophenyl)-7-phenylimidazo[1,5-f][...)
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275699BDBM50275699(7-(2-methoxyphenyl)-5-methyl-N-(3,4,5-trimethoxyph...)
Affinity DataIC50: 5.66E+3nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275591BDBM50275591(5-methyl-7-phenyl-N-(2-(pyridin-4-yl)ethyl)imidazo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275590BDBM50275590(5-methyl-7-phenylimidazo[1,5-f][1,2,4]triazin-2-am...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275624BDBM50275624(N-cyclohexyl-5-methyl-7-phenylimidazo[1,5-f][1,2,4...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275592BDBM50275592(5-methyl-N-(3-morpholinopropyl)-7-phenylimidazo[1,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50275661BDBM50275661(5-methyl-7-phenyl-N-(3-(trifluoromethyl)phenyl)imi...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1 expressed in baculovirus infected Trichoplusia ni cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed