Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50027445
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human procollagen C-proteinase expressed in CHO cells by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256367((R)-2-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256368((R)-2-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256203((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256303((R)-2-(5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256306((R)-6-cyclohexyl-N-hydroxy-3-(3-(morpholine-4-carb...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256305((R)-6-cyclohexyl-N-hydroxy-3-(3-(piperidine-1-carb...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256150((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256151((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256204((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216798((R)-ethyl 5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohe...)
Affinity DataIC50:  36nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256302((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256096((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256304((R)-6-cyclohexyl-N-hydroxy-3-(3-(pyrrolidine-1-car...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256207((R)-2-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256365((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256205((R)-N-benzyl-5-(6-cyclohexyl-1-(hydroxyamino)-1-ox...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256366((R)-N-benzyl-5-(6-cyclohexyl-1-(hydroxyamino)-1-ox...)
Affinity DataIC50:  65nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256206((R)-2-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097252((R)-N'-((S)-3,3-dimethyl-1-oxo-1-((R)-1-phenylethy...)
Affinity DataIC50:  135nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50:  820nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50:  900nMAssay Description:Inhibition of PDE4DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097259((R)-2-(3-Cyclohexyl-propyl)-N*1*-[(S)-2,2-dimethyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of PDE4BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of PDE4AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256149((S)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of PDE4CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216835((R)-ethyl 5-(1-(hydroxyamino)-1-oxo-6-phenylhexan-...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216835((R)-ethyl 5-(1-(hydroxyamino)-1-oxo-6-phenylhexan-...)
Affinity DataIC50:  6.60E+3nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBone morphogenetic protein 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50097252((R)-N'-((S)-3,3-dimethyl-1-oxo-1-((R)-1-phenylethy...)
Affinity DataIC50:  8.77E+3nMAssay Description:Inhibition of human procollagen C-proteinase assessed as [3H]procollagen turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MMP9 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MMP14 catalytic domain by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MMP3 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of interstitial MMP1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256151((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  2.17E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human MMP3 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256150((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256204((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256302((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256096((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50:  5.05E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216795((3R)-6-cyclohexyl-N-hydroxy-3-(1,2,4-oxadiazol-5-y...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256305((R)-6-cyclohexyl-N-hydroxy-3-(3-(piperidine-1-carb...)
Affinity DataIC50:  7.49E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50216798((R)-ethyl 5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohe...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256366((R)-N-benzyl-5-(6-cyclohexyl-1-(hydroxyamino)-1-ox...)
Affinity DataIC50:  8.18E+4nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256303((R)-2-(5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50256203((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50241177((R)-5-(6-cyclohexyl-1-(hydroxyamino)-1-oxohexan-3-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human MMP2 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed