Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50027581
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256384BDBM50256384(6-chloro-N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256383BDBM50256383(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256322BDBM50256322(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25472BDBM25472(N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benz...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256436BDBM50256436(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50246409BDBM50246409(N-(4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256067BDBM50256067(N3-(4-(1H-pyrazol-4-yl)phenyl)-N6-(2-(dimethylamin...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256166BDBM50256166(N-(4-(1H-pyrazol-4-yl)phenyl)-6-methoxychroman-3-c...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256163BDBM50256163(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256068BDBM50256068(6-methoxy-N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)c...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256069BDBM50256069(6-methoxy-N-(2-methoxy-4-(1H-pyrazol-4-yl)phenyl)c...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256111BDBM50256111(N-(2-methoxy-4-(1H-pyrazol-4-yl)phenyl)chroman-3-c...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256385BDBM50256385(6-chloro-N-(2-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256382BDBM50256382(6-fluoro-N-(2-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256113BDBM50256113(N-(3,5-difluoro-4-(1H-pyrazol-4-yl)phenyl)chroman-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256223BDBM50256223(N-(4-(1H-pyrazol-4-yl)phenyl)-6-fluorochroman-3-ca...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256435BDBM50256435(N-(2-methoxy-4-(1H-pyrazol-4-yl)phenyl)-6-methylch...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256112BDBM50256112(N-(2-fluoro-4-(1H-pyrazol-4-yl)phenyl)chroman-3-ca...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256110BDBM50256110(N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)chroman-3-c...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256114BDBM50256114(N-(5-fluoro-2-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256224BDBM50256224(N-(4-(1H-pyrazol-4-yl)phenyl)-6-chlorochroman-3-ca...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256386BDBM50256386(6-chloro-N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyra...)
Affinity DataIC50: 5nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256323BDBM50256323(6-fluoro-N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...)
Affinity DataIC50: 7nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256225BDBM50256225(N-(4-(1H-pyrazol-4-yl)phenyl)-6-methylchroman-3-ca...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256066BDBM50256066(methyl 3-(4-(1H-pyrazol-4-yl)phenylcarbamoyl)chrom...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256434BDBM50256434(N-(3-methoxy-4-(1H-pyrazol-4-yl)phenyl)-6-methylch...)
Affinity DataIC50: 12nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256162BDBM50256162(N-(2-fluoro-5-methoxy-4-(1H-pyrazol-4-yl)phenyl)ch...)
Affinity DataIC50: 17nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256226BDBM50256226(3-(4-(1H-pyrazol-4-yl)phenylcarbamoyl)chroman-6-ca...)
Affinity DataIC50: 30nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256321BDBM50256321(N-(4-(1H-pyrazol-4-yl)phenyl)-6-(4-methylpiperazin...)
Affinity DataIC50: 78nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256383BDBM50256383(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 79nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256227BDBM50256227(N3-(4-(1H-pyrazol-4-yl)phenyl)-N6,N6-dimethylchrom...)
Affinity DataIC50: 86nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256320BDBM50256320(N3-(4-(1H-pyrazol-4-yl)phenyl)-N6-(2-(dimethylamin...)
Affinity DataIC50: 93nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256322BDBM50256322(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 150nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase MRCK alpha(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256163BDBM50256163(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 210nMAssay Description:Inhibition of MRCKalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256165BDBM50256165(N-(4-(1H-pyrazol-4-yl)phenyl)-8-methoxychroman-3-c...)
Affinity DataIC50: 285nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256164BDBM50256164(N-(3-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 640nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256163BDBM50256163(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256322BDBM50256322(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256383BDBM50256383(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256322BDBM50256322(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256383BDBM50256383(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50256163BDBM50256163(N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed